... evidence in human (or more generally, diploid) genetic studies. In terms of scope, KELVIN supports two-point (trait-marker or marker-marker) and multipoint linkage analysis, based on either sex-averaged or sex-specific genetic maps, with an option to allow for imprinting; trait-marker linkage...

... to in the content or advertisements. Preterm birth Gestational age Segregation analysis Maternal effects Imprinting Genetic model National Institutes of Health (NIH) 10.13039/100000002 Original Paper Hum Hered 2009;68:209 219 DOI: 10.1159/000224641 Received: December 9, 2008 Accepted...

...Sanjay Shete; Xiaojun Zhou Objectives: Imprinting refers to the expression of only one copy of a gene pair, which is determined by the parental origin of the copy. Imprinted genes play a role in the development of several complex diseases, including cancers and mental disorders. In certain...

...Tim Becker; Max P. Baur; Michael Knapp Despite the potential pitfalls of stratification, population-based association studies nowadays are being conducted more often than family-based association studies. However, the mechanism of genomic imprinting has lately been implicated in the etiology...

...Sanjay Shete; Xiaojun Zhou Genomic imprinting is a mechanism by which only one copy of a gene pair is expressed, and this expression is determined by the parental origin of the copy. The deregulation of imprinted genes has been implicated in a number of human diseases. The Imprinted Gene Catalogue...

... of basic biology and can increase the power of a linkage study, improve gene localization, and provide clues to possible imprinting. One way to detect these differences is to use lod scores. In this study we focused on detecting RF sex differences and answered the following questions, in both phase-known...