.... We test hypotheses regarding killer cell immunoglobulin-like receptor (KIR) and HLA-C MFG effects on human birth weight by extending the quantitative MFG (QMFG) test. Methods: Until recently, association testing for MFG interactions had limited applications. To improve the ability to test...

...Alicia Sanchez-Mazas; Stéphane Buhler; José Manuel Nunes Objectives: HLA genes are highly polymorphic in human populations as a result of diversifying selection related to their immune function. However, HLA geographic variation worldwide suggests that demographic factors also shaped...

...J.M. Bryttan; D.D. Kostyu; C. Ober; S. Elias; D.V. Dawson HLA data from 1,085 South Dakotan Schmiedeleut Hutterites were examined for evidence of nonrandom transmission of haplotypes. The inheritance of haplotypes was viewed as a series of genetic contests between competing pairs of parental...

...Z. Faghiri; S.Z. Tabei; F. Taheri HLA class I antigen frequencies were studied in 52 patients with kala-azar and compared with 222 unrelated healthy controls. The relative risk (RR) and etiologic or preventive fraction (EF/PF) were determined for each character, and statistical significance...

...Mary S. Hayney; Gregory A. Poland; James J. Lipsky Buccal-cell-derived DNA collected by a ‘swish and spit’ technique and blood-derived DNA were compared for ease of collection, participant acceptance, utility and accuracy for HLA class II DR typing by the polymerase chain reaction with sequence...

...S.S. Papiha; M.F. Duggan-Keen; R.S.E. Rodger In the population of north-east England gene frequencies of DR antigens and Bf alleles were investigated. The available data from Britain were examined for genetic heterogeneity. 2 9 2008 HLA DR antigens Bf types Hum. Hered. 35: 246-249...

...R.W.C. Haile; L. Iselius; P.E.M. Fine; N.E. Morton Data on 72 families with multiple cases of leprosy were analyzed for a susceptibility gene linked to the HLA loci. We conducted segregation analysis with the program POINTER and identity of HLA types by descent analysis to determine the most likely...

... tumors being rarely seen. The recent localization of the prolactin structural gene to chromosome 6 made further investigation of linkage to HLA of particular interest. Results in 2 multigeneration families exclude close linkage to HLA. We cannot at this time draw any inference regarding linkage of MEN I...

... are discussed. 2 9 2008 HLA Linkage Sib pairs Multiple case families Hum. Hered. 33: 244-249 (1983) © I >83 S. Karger AG. Base! 0001-5652/83/0334-0244 $ 2.75/0 An Exact Linkage Test for Multiple Case Families N.E. Morton Population Genetics Laboratory. University of Hawaii. Honolulu, Hawaii...

...Linda J. Walsh; Robert M. Ehrlich; Judy A. Falk; Nancy E. Simpson The hypothesis of linkage between HLA and a disease susceptibility (DS) locus (or loci) for type 1 diabetes was tested. HLA segregation was random among 57 non-diabetic sibs but not among 39 diabetic sibs, suggesting...

... at the HLA loci. 2 9 2008 © 1983 S. Karger AG, Basel 1983 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including...

.... Paternity testing Blood group HLA DNA markers Biostatistical evaluation Classical paternity exclusion α 1 -Antitrypsin Mutation Intracistronal crossing-over Original Papers Hum Hered 1991;41:1-11 © 1991 S. Karger AG. Basel 0001-5652/91/0411-0001 S 2.75/0 New Mutation versus Exclusion...

... kb and 5.5 kb allele were 0.73 and 0.27, respectively. The 5.5 kb band was significantly positively associated with HLA-A1, B8, DRI7.1, and C4AQ0, and negatively associated with DR7.2, DQw9 and C4A6, all being specificities which belong to two well-known Caucasoid ancestral haplotypes. When...

...Christina Rudduck; Göran Franzén; Bengt Löw; Birgitta Rorsman Frequencies of HLA A, B, C, and DR antigens were studied in 100 schizophrenic patients and 919 controls from South Sweden. The patients were diagnosed according to the DSM III criteria and divided into four clinical subgroups...

...E. Olivetti; S. Rendine; N. Cappello; E.S. Curtoni; A. Piazza 4,902 Italians were typed for HLA-A antigens, 4,721 for HLA-B and 1,503 for HLA-C. The samples, which were composed of unrelated, healthy individuals born in Italy, were used for estimating HLA-A, HLA-B and HLA-C gene frequencies...

...Richard R. Fabsitz; Jun-mo Nam; John Gart; Albert Stunkard; Arlen Price; Peter W.F. Wilson A subgroup of 351 subjects with human leukocyte antigen (HLA) typing were available from the Framingham Heart Study for analyses to identify associations with obesity. The subjects consisted of 143 males...

...Maarten J. Nauta; Rob van Treuren; Leo P. ten Kate; Gerard J. te Meerman; Joe D’ Amaro We compared family distances of homozygotes and heterozygotes for HLA-A and -B. When matched on number of inhabitants per birthplace, no significant differences were found. However, when homozygotes were compared...

...Arlene F. Kantor A procedure for estimating HLA phenotype frequencies from two- and three-locus haplotype frequencies is described. Formulae for this procedure are derived, and examples are presented to illustrate the application. The procedure is useful when multiple-locus phenotype frequencies...

... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chimerism Blood groups HLA Chromosomes...

...E.J.C. Haas; F.M. Salzano; H.A. Araujo; F. Grossman; A. Barbett; T.A. Weimer; M.H.L.P. Franco; L. Verruno; O. Nasif; V.H. Morales; R. Arienti A total of 107 Mapuche Indians living in western Argentina were studied with respect to 16 genetic systems. For HLA, there were a few differences in relation...