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Keywords: Genomic control
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Journal Articles
Subject Area:
Genetics
Hum Hered (2013) 76 (1): 28–35.
Published Online: 31 July 2013
... existing methods (principal component analysis and genomic control) to correct for stratification in such rare-variant studies. Results: We found that population stratification can have a significant influence on studies of rare variants especially when the sample size is large and the population...
Journal Articles
Subject Area:
Genetics
Hum Hered (2010) 69 (4): 285–294.
Published Online: 14 April 2010
... to genomic control (GC) under valid simulation conditions; and to highlight other studies employing similarly flawed simulations. Methods: DC and GC use data from unlinked null loci to correct the test statistic at the target locus, but differ in the way the correction is performed. We compare DC and GC...
Journal Articles
Journal Articles
Subject Area:
Genetics
Hum Hered (2007) 64 (3): 149–159.
Published Online: 25 May 2007
... 0.653 is medium, and a δ of size 1.115 is large). A novel feature of our testing procedure is its ability to test for either strictly any PS or only ‘practically important’ PS. We also performed simulations to compare our correction procedure with Genomic Control (GC). Our results show that, unlike GC...
Journal Articles
Journal Articles
Subject Area:
Genetics
Hum Hered (2005) 58 (3-4): 145–153.
Published Online: 21 March 2005
...Dvora Shmulewitz; Junying Zhang; David A. Greenberg Objective: Case-control association studies in mixed populations can result in spurious disease-marker associations if subpopulation disease prevalence and marker frequencies both differ. Genomic control (GC) uses neutral loci to correct...
Journal Articles
Subject Area:
Genetics
Hum Hered (2005) 58 (2): 93–107.
Published Online: 10 February 2005
... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Population stratification Lateral class analysis Structured association Genomic control...