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Keywords: Genetic association studies
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Journal Articles

Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits

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Subject Area:
Genetics
Dana C. Crawford, Robert Goodloe, Eric Farber-Eger, Jonathan Boston, Sarah A. Pendergrass, Jonathan L. Haines, Marylyn D. Ritchie, William S. Bush
Journal: Human Heredity
Hum Hered (2015) 79 (3-4): 137–146.
https://doi.org/10.1159/000381805
Published Online: 28 July 2015
... to in the content or advertisements. Hispanics Bias Genetic association studies EAGLE BioVU NHANES Electronic medical records African Americans National Institutes of Health (NIH) 10.13039/100000002 Original Paper Hum Hered 2015;79:137 146 DOI: 10.1159/000381805 Published online: July 28...
View articletitled, Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits
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Journal Articles

A Network-Based Kernel Machine Test for the Identification of Risk Pathways in Genome-Wide Association Studies

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Subject Area:
Genetics
Saskia Freytag, Juliane Manitz, Martin Schlather, Thomas Kneib, Christopher I. Amos, Angela Risch, Jenny Chang-Claude, Joachim Heinrich, Heike Bickeböller
Journal: Human Heredity
Hum Hered (2014) 76 (2): 64–75.
https://doi.org/10.1159/000357567
Published Online: 14 January 2014
... arthritis Disease association Genetic association studies National Institutes of Health (NIH) 10.13039/100000002 Original Paper Hum Hered 2013;76:64 75 DOI: 10.1159/000357567 Received: August 26, 2013 Accepted after revision: November 26, 2013 Published online: January 14, 2014 A Network...
View articletitled, A Network-Based Kernel Machine Test for the Identification of Risk Pathways in Genome-Wide Association Studies
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Journal Articles

Individual Genetic Variations Related to Satiety and Appetite Control Increase Risk of Obesity in Preschool-Age Children in the STRONG Kids Program

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Subject Area:
Genetics
Yingying Wang, Anthony Wang, Sharon M. Donovan, Margarita Teran-Garcia, and the STRONG Kids Research Team
Journal: Human Heredity
Hum Hered (2013) 75 (2-4): 152–159.
https://doi.org/10.1159/000353880
Published Online: 27 September 2013
..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Childhood obesity Genetic scores Breastfeeding Genetic association studies...
View articletitled, Individual Genetic Variations Related to Satiety and Appetite Control Increase Risk of Obesity in Preschool-Age Children in the STRONG Kids Program
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Journal Articles

Incorporating Prior Biologic Information for High-Dimensional Rare Variant Association Studies

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Subject Area:
Genetics
Melanie A. Quintana, Fredrick R. Schumacher, Graham Casey, Jonine L. Bernstein, Li Li, David V. Conti
Journal: Human Heredity
Hum Hered (2013) 74 (3-4): 184–195.
https://doi.org/10.1159/000346021
Published Online: 11 April 2013
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Genetic association studies Bayesian model uncertainty Bayes factors Sequence analysis Rare variant analysis...
View articletitled, Incorporating Prior Biologic Information for High-Dimensional Rare Variant Association Studies
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Journal Articles

Natural and Orthogonal Interaction Framework for Modeling Gene-Environment Interactions with Application to Lung Cancer

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Subject Area:
Genetics
Jianzhong Ma, Feifei Xiao, Momiao Xiong, Angeline S. Andrew, Hermann Brenner, Eric J. Duell, Aage Haugen, Clive Hoggart, Rayjean J. Hung, Philip Lazarus, Changlu Liu, Keitaro Matsuo, Jose Ignacio Mayordomo, Ann G. Schwartz, Andrea Staratschek-Jox, Erich Wichmann, Ping Yang, Christopher I. Amos
Journal: Human Heredity
Hum Hered (2012) 73 (4): 185–194.
https://doi.org/10.1159/000339906
Published Online: 09 August 2012
... advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Statistical power Genetic association studies...
View articletitled, Natural and Orthogonal Interaction Framework for Modeling Gene-Environment Interactions with Application to Lung Cancer
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Journal Articles

Missing Heritability in the Tails of Quantitative Traits? A Simulation Study on the Impact of Slightly Altered True Genetic Models

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Subject Area:
Genetics
Carolin Pütter, Sonali Pechlivanis, Markus M. Nöthen, Karl-Heinz Jöckel, Heinz-Erich Wichmann, André Scherag
Journal: Human Heredity
Hum Hered (2011) 72 (3): 173–181.
https://doi.org/10.1159/000332824
Published Online: 25 October 2011
.... Selective sampling Heritability Genetic association studies Mixture distribution ...
View articletitled, Missing Heritability in the Tails of Quantitative Traits? A Simulation Study on the Impact of Slightly Altered True Genetic Models
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Journal Articles

On Combining Triads and Unrelated Subjects Data in Candidate Gene Studies: An Application to Data on Testicular Cancer

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Subject Area:
Genetics
Li Hsu, Jacqueline R. Starr, Yingye Zheng, Stephen M. Schwartz
Journal: Human Heredity
Hum Hered (2009) 67 (2): 88–103.
https://doi.org/10.1159/000179557
Published Online: 12 December 2008
... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Genetic association studies Family...
View articletitled, On Combining Triads and Unrelated Subjects Data in Candidate Gene Studies: An Application to Data on Testicular Cancer
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Journal Articles

A Family-Based Likelihood Ratio Test for General Pedigree Structures That Allows for Genotyping Error and Missing Data

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Subject Area:
Genetics
Yang Yang, Carol A. Wise, Derek Gordon, Stephen J. Finch
Journal: Human Heredity
Hum Hered (2008) 66 (2): 99–110.
https://doi.org/10.1159/000119109
Published Online: 31 March 2008
... from any ideas, methods, instructions or products referred to in the content or advertisements. Family based association study Genetic association studies Missing data TDT-like tests Original Paper Hum Hered 2008;66:99 110 DOI: 10.1159/000119109 Published online: March 31, 2008 A Family...
View articletitled, A Family-Based Likelihood Ratio Test for General Pedigree Structures That Allows for Genotyping Error and Missing Data
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Journal Articles

Accounting for Relatedness in Family Based Genetic Association Studies

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Subject Area:
Genetics
P.F. McArdle, J.R. O’Connell, T.I. Pollin, M. Baumgarten, A.R. Shuldiner, P.A. Peyser, B.D. Mitchell
Journal: Human Heredity
Hum Hered (2007) 64 (4): 234–242.
https://doi.org/10.1159/000103861
Published Online: 14 June 2007
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Genetic association studies Type 1 error Variance components Regression modeling National Institutes of Health (NIH) 10.13039/100000002 Original Paper Hum...
View articletitled, Accounting for Relatedness in Family Based Genetic Association Studies
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Journal Articles

Haplotype Sharing Analysis Using Mantel Statistics

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Subject Area:
Genetics
L. Beckmann, D.C. Thomas, C. Fischer, J. Chang-Claude
Journal: Human Heredity
Hum Hered (2005) 59 (2): 67–78.
https://doi.org/10.1159/000085221
Published Online: 17 May 2005
... Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany; b University of Southern California, Los Angeles, Calif., USA Key Words Haplotype sharing Mantel statistics Case-control studies Genetic association studies Complex disease Abstract Objective: The potential value...
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Journal Articles

Evidence of Admixture from Haplotyping in an Epidemiological Study of UK Caucasian Males: Implications for Association Analyses

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Subject Area:
Genetics
Xiao-he Chen, Santiago Rodríguez, Emma Hawe, Philippa J. Talmud, George J. Miller, Peter Underhill, Stephen E. Humphries, Ian N.M. Day
Journal: Human Heredity
Hum Hered (2004) 57 (3): 142–155.
https://doi.org/10.1159/000079245
Published Online: 10 August 2004
...Xiao-he Chen; Santiago Rodríguez; Emma Hawe; Philippa J. Talmud; George J. Miller; Peter Underhill; Stephen E. Humphries; Ian N.M. Day Objective: Cohort and case-control genetic association studies offer the greatest power to detect small genotypic influences on disease phenotypes, relative...
View articletitled, Evidence of Admixture from Haplotyping in an Epidemiological Study of UK Caucasian Males: Implications for Association Analyses
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