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Keywords: Gene-environment interaction
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Journal Articles
Subject Area:
Genetics
Hum Hered (2020) 84 (3): 117–126.
Published Online: 19 December 2019
... when heterogeneity is high. The new method can increase the probability of finding novel SNP-environment interaction. MR is a powerful and robust method for testing gene-environment interaction in GWASs. It can be used for dichotomous and continuous environmental exposures and can be flexibly...
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Genetics
Hum Hered (2010) 70 (1): 23–33.
Published Online: 23 April 2010
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Haplotype-environment interaction Gene-environment interaction Case-parent triad Permutation test Non-parametreic test Population stratification National...
Journal Articles
Journal Articles
Journal Articles
Subject Area:
Genetics
Hum Hered (2008) 66 (3): 170–179.
Published Online: 20 May 2008
... of disease. This study investigates the influence of gene-environment interactions on the relative risks of disease for the offspring and the spouses of affected individuals. Methods: Theoretical models were developed to explore the dependence of familial relative risks on environmental parameters (exposure...
Journal Articles
Subject Area:
Genetics
Hum Hered (2007) 65 (3): 154–165.
Published Online: 12 October 2007
... or clinical covariates may contribute to disease risk or linkage heterogeneity: (i) a quantitative trait locus (QTL) underlying a continuous disease risk factor, (ii) a gene-environment interaction model, (iii) a heterogeneity model defined by distinct covariate distributions in linked and unlinked families...
Journal Articles
Subject Area:
Genetics
Hum Hered (2007) 65 (1): 1–8.
Published Online: 25 July 2007
... Haplotype ALOX15 Osteoporosis Genetic association Chinese Gene-environment interaction Original Paper Hum Hered 2008;65:1 8 DOI: 10.1159/000106057 Received: February 5, 2007 Accepted after revision: March 23, 2007 Published online: July 25, 2007 A Differential Association of ALOX15 Polymorphisms...
Journal Articles
Subject Area:
Genetics
Hum Hered (2007) 64 (1): 5–15.
Published Online: 27 April 2007
... trait Breast cancer Covariate Gene-environment interaction Migraine Original Paper Hum Hered 2007;64:5 15 DOI: 10.1159/000101418 Published online: April 27, 2007 Score Test for Linkage in Generalized Linear Models J.J.P. Lebreca, b H.C. van Houwelingena aDepartment of Medical Statistics...
Journal Articles
Subject Area:
Genetics
Hum Hered (2007) 63 (3-4): 212–218.
Published Online: 07 March 2007
.... AMD Environmental risk factor Epidemiologic approaches Gene-environment interaction Genotype Macular degeneration Original Paper Hum Hered 2007;63:212 218 DOI: 10.1159/000100046 Received: October 13, 2006 Accepted after revision: January 4, 2007 Published online: March 7, 2007 The LOC387715...
Journal Articles
Journal Articles
Subject Area:
Genetics
Hum Hered (2006) 61 (3): 157–165.
Published Online: 16 August 2006
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Case-control association analysis Environmental risk factor Epidemiologic approaches Gene-environment interaction...
Journal Articles
Subject Area:
Genetics
Hum Hered (2003) 56 (1-3): 94–106.
Published Online: 14 November 2003
... Linkage analysis W Genetic heterogeneity W Locus heterogeneity W Gene-environment interaction W Gene-gene interaction W Likelihood ratio test W Two-sample t test W Incomplete data W Parameter constraints Abstract Objectives: Modelling of variation in identical-by-descent (IBD) allele sharing using...
Journal Articles
Subject Area:
Genetics
Hum Hered (2003) 55 (1): 56–65.
Published Online: 06 August 2003
... covariates. For these purposes, tests of gene-environment interactions are needed. In addition, recent studies have indicated that haplotypes, which are specific combinations of nucleotides on the same chromosome, may be more suitable as the unit of analysis for statistical tests than single genetic markers...
Journal Articles
Journal Articles
Subject Area:
Genetics
Hum Hered (2000) 50 (5): 271–285.
Published Online: 20 June 2000
... unusual transmission patterns in families. Since phenotypic similarity can also be caused by environmental similarity, we investigate how the presence of gene-environment interaction (GEI) affects the power of both methods. For a simple one-locus-one-risk-factor model, our results indicate...