... genotypes · Missing data · Family studies · Family data · Association tests Abstract Background: In longitudinal epidemiological studies there may be individuals with rich phenotype data who die or are lost to follow-up before providing DNA for genetic studies. Often, the genotypic and phenotypic data...

... and relative risk values around 3, at an α level of 10 -11 ). When cases are ascertained in a sample of cases having an affected sib, the use of linkage information in our test allows a gain of power of more than 20% in certain situations. Conclusion: We demonstrate the interest in using familial data and both...

...Xiang Li; Saonli Basu; Michael B. Miller; William G. Iacono; Matt McGue Genome-wide association studies (GWAS) using family data involve association analyses between hundreds of thousands of markers and a trait for a large number of related individuals. The correlations among relatives bring...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Haplotype inference Pedigree Family data Original Paper Hum Hered 2009;67:248 266 DOI: 10.1159/000194978 Received: January 31, 2008 Accepted after revision: August 8...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Family data Likelihood Haplotypes Latent disease locus Alzheimer Original Paper Hum...

...George Ebow Bonney The regressive models for the analysis of family data are extended to include cases in which the within-sibship covariation may exceed that implied by the class A regressive model, but for which birth order is not required. In addition to specified major genes, if any, and common...

... system Protease inhibitor Isoelectric focusing PiM subtypes Inheritance Family data Hum. Hered. 29: 351-354 (1979) Inheritance of PiM Subtypes A Study of 151 Families with a Total of 242 Children and of 142 Mother-Child Pairs H. Cleve, W. Patutschnick, K. Strecker and S. Nevo Institut für...

.... Segregation analysis Incomplete ascertainment Family data Abstract. The properties of a test, suggested by Haldane [1938], for a Mendelian segregation ratio of 0.25 when ascertainment is incomplete are investigated. The error rates associated with this procedure show the weakness of this specific test...

...G. Sorgo The occurrence of the variant group-specific component Gc Z in a further family is reported. Gc z Family data 28 8 2008 © 1975 S. Karger AG, Basel 1975 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated...

...Yuanjia Wang; Yixin Fang; Man Jin Objective: To develop a ridge penalized principal-components approach based on heritability that can be applied to high-dimensional family data. Methods: The first principal component of heritability for a trait constellation is defined as a linear combination...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Genotyping errors Haplotype frequency Population data Family data...