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Keywords: Extreme sampling
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Journal Articles
Subject Area:
Genetics
Hum Hered (2012) 73 (2): 105–122.
Published Online: 28 April 2012
...: It is demonstrated that when extreme sampling is implemented within equal-sized cohorts of unrelated individuals or sib-pairs, analyzing unrelated individuals is consistently more powerful than studying sib-pairs. A higher portion of rare variants can be identified through sequencing unrelated samples compared...
Journal Articles
Subject Area:
Genetics
Hum Hered (2000) 51 (1-2): 35–40.
Published Online: 30 October 2000
..., instructions or products referred to in the content or advertisements. Risk ratio Lambda Overweight Obesity Body mass index Extreme sampling Discordant pairs Overweight and obesity are very common health problems, currently affecting one third to one half of adults in the United States [ 1...
Journal Articles
Subject Area:
Genetics
Hum Hered (1998) 48 (2): 97–107.
Published Online: 18 February 1998
... papers have demonstrated that such extreme sampling can markedly increase power (under certain circumstances). However, the parenthetical phrase in the previous sentence has generally not been made explicit and it appears to be implied that the more phenotypically extreme the individuals, the more power...