... interactions and covariate effects. Features and data (pedigree) structures can be freely mixed and matched within analyses. The statistical framework is specifically tailored to accumulate evidence in a mathematically rigorous way across multiple data sets or data subsets while allowing for multiple sources...

.... 17 5 2002 Model-free analysis Sib pair, affected Epistasis Interaction Covariates Original Paper Hum Hered 2002;53:92 102 Received: September 17, 2001 Revision received: January 24, 2002 Accepted: January 25, 2002 Detecting Gene-Gene Interactions Using Affected Sib Pair Analysis...