The genetic polymorphism of eight red cell enzymes was analyzed in four population samples from the two easternmost islands of the Canary Archipelago. No heterogeneity was detected within the islands, but differences between them were of the same magnitude as those found between the islands and the Spanish mainland. The presence of the African G6PD-A+ and the rare G6PD-Gc alleles seems to be a characteristic of all Canarian populations studied.

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