The distribution of the phenotypes of the red cell enzymes adenosine deaminase (EC 3.5.4.4), esterase D, glutamate pyruvate transaminase (EC 2.6.1.2) and galactose-1-phosphate-uridyltransferase (EC 2.7.7.12), were studied on a large number of Swiss individuals. The phenotypes of all four enzymes were found to be distributed according to the Hardy-Weinberg law, although levels of statistical significance of the differences were not of the same order for all four enzymes. Gene frequencies were calculated and found to be in good agreement with data from the literature concerning the Caucasian populations. Among numerous mother-child pairs, no phenotype constellations that were in contradiction to the genetical hypothesis were observed. Phenotypes were distributed identically in men and women.

Keywords:
Adenosine deaminase, Esterase D, Glutamate pyruvate transaminase, Galactose-1-phosphate-Uridyltransferase, Gene frequencies, Swiss population
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© 1976 S. Karger AG, Basel
1976
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