Experiments show that the GPT starch gel pattern of any given blood sample is fully reproducible, and that an individual’s GPT type is constant at least after the age of 1 month. GPT isoenzyme patterns are influenced and may be changed during storage of unfrozen blood. The interval between sampling and preparation of haemolysate should therefore not exceed 4 days. In haemolysates kept at –25 °C the isoenzyme patterns remain unchanged for at least many months. The GPT system forms a valuable means for statistical information in paternity cases. Thus, the overall chance is 18.7% for paternity exclusion or strong evidence against paternity for a falsely alleged father. Based on a material of 1,316 paternity cases, it is concluded that the GPT system is a valuable supplement to other systems of genetic markers in cases of disputed paternity.

Keywords:
GPT system, Genetics, Paternity cases
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© 1975 S. Karger AG, Basel
1975
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