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Keywords: Repeated significance test
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Journal Articles
Journal: Heart Drug
Heart Drug (2003) 3 (2): 113–116.
Published Online: 20 August 2003
...Eva Skovlund The main purpose of performing interim analyses in a clinical trial is to stop the trial once a convincing treatment difference can be demonstrated. The major problem with repeated significance tests during inclusion and/or follow-up in a clinical trial is that the more often one...