... reduced its glucose-6-phosphatase activity, caused only a small decrease in the aromatizing activity of this fraction. In incubations with 4-androstene-3,17-dione, testosterone and 3Β-hydroxy-5-androstene-17-one, the ratio of 17Β-estradiol to estrone produced was greater with the microsomal ( > 2.00...

... of testosterone synthesis occurred over a time range consistent with the duration of sterility. The results also indicated that the metabolism of pregnenolone and 17Α-hydroxyprogesterone are impaired. 19 3 2010 © 1971/1972 S. Karger AG, Basel 1971 Copyright / Drug Dosage / Disclaimer Copyright...

...A. Gillespie Scrotal skin converts more testosterone to 5Α-dihydro-testosterone than normal labial skin. Labial skin from a patient with androgen insensitivity carried out the conversion in amounts similar to normal labial skin. Labial skin of 3 XY female patients with streak gonads carried out...

...R. Massa; L. Martini The paper presents evidence indicating that, in an “in vitro” system, progesterone may interfere with the conversion of testosterone into its “active” metabolites (5 alpha-androstan-17 beta-ol-3-one, 5 alpha-androstan-3 beta, 17 beta-diol and 5 alpha-androstan-3 alpha, 17 beta...

...R.E. Mancini; Pé;rez Lloret; A. Guitelman; J. Ghirlanda A group of adult hypophysectomized patients (due to cromophobe adenoma) was studied at different periods of time after operation. All of them showed loss of libido and potentia, low levels of urinary FSH and LH and of testosterone glucoronide...

...-pregnene-3-one, was consistently secreted by the corpus luteum. Small amounts of estrone and testosterone may be secreted by the ovary. In two ases with bilateral ovulation, there was a similarity between the steroid output of the two corpora lutea. In one subject studied following clomiphene treatment...

... on the uptake of oestradiol and testosterone. Histamine increased the uptake of labelled oestradiol by the uterus and the hypothalamus. When histamine effects were studied in relation with testosterone uptake, it increased the hypothalamic, but not the uterine uptake. Even knowing that the mammalian pineal...

...Harlan R. Giles; Charles D. Lox; Wayne Heine; C.D. Christian Amniotic fluid testosterone levels were measured by a sensitive and specific radioimmunoassay technique from 75 term pregnancies and from 57 pregnancies prior to 20 weeks gestation. Statististically significant differences (p < 0.05...

... studies showed that testosterone was the principal secretory product of tumor cells. Androstenedione, 17-hydroxyprogesterone, and dehydroepiandrosterone sulfate were normal. Light and electron microscopic investigations of the tumor showed polygonal cells containing intracytoplasmic Reinke crystalloids...

... and oestriol, brings about neoplasia. There is also some evidence of a protective effect of androgens and progesterone. In order to verify this theory in vivo, oestrone (E 1 ), oestradiol (E 2 ), testosterone (T) and progestogen levels were examined from the serum of 36 post-menopausal women suffering from...

...Nobuaki Furuhashi; Takao Fukaya; Hideaki Kono; Yoshinobu Tachibana; Osamu Shinkawa; Toru Takahashi Luteinizing hormone-human chorionic gonadotropin (LH-hCG), follicle-stimulating hormone (FSH), Β-human chorionic gonadotropin (Β-hCG), estradiol, cortisol and testosterone levels were determined...

.... 29 02 1988 23 03 1988 2 3 2010 Lipid cell tumor Hilus cell tumor 75 Se-selenomethylcholesterol Androgens Testosterone Androstenedione Hirsutism Virilization Ovarian tumor © 1989 S. Karger AG, Basel 1989 Copyright / Drug Dosage / Disclaimer Copyright: All rights...

...Susumu Terada; Nobutaka Suzuki; Kiyoshi Uchide; Kazutomo Akasofu; Etsuro Nishida In order to study the effect of testosterone on bladder calculi and tumor formation in female rats, Wistar rats were administered testosterone for 12, 18 or 24 weeks. Testosterone was found to increase the incidence...

... were divided into two subgroups: 17 with high serum total testosterone (T) level ( > 0.5 ng/ml) and 14 with normal serum total T level ( < 0.5 ng/ml). Both subgroups presented for the complaints of oligomenorrhea and/or hirsutism. The control group consisted of 15 women with regular ovulation...

...A.N. Elias; M.R. Pandian; F.-J. Rojas Serum concentrations of androstenedione, testosterone and dehydroepiandrosterone sulfate (DHEAS) were measured in 29 patients with premature ovarian failure (POF) and an identical number of age-matched normal control subjects. The study was aimed at determining...

... containing estriol, estradiol, progesterone, DHEA, and testosterone. Methods: A combination cream was administered to 12 postmenopausal women in two differing doses over two independent time periods. Following 28 days (arm 1) and an additional 14 days (arm 2), measurement of hormones in saliva and blood...