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Subject Area:Topic Article Package: Antibody-Drug Conjugates , Further Areas , Women's and Children's Health
Gynecol Obstet Invest (2023) 88 (3): 159–167.
Published Online: 27 June 2023
...Lidan He; Qiongfang Song; Jifen Hu; Jianbo Wu Objectives: Placental inflammation possibly underlies preeclampsia (PE) pathogenesis. This study aimed to investigate the expression of the high mobility box group 1 (HMGB1)-toll-like receptor 4 (TLR4) signalling pathway in preeclamptic placentas...
Gynecol Obstet Invest (2022) 87 (5): 305–315.
Published Online: 05 October 2022
...Yubo Shi; Lianxiao Zhang; Linlin Wang; Huiqing Ding Objective: Preeclampsia (PE) is the most common gestational disease related to various biomolecules, including circular RNA. Hsa_circ_0088196 (circ_0088196) was aberrantly upregulated in PE tissues. Design: This study focused on the further...
Gynecol Obstet Invest (2022) 86 (6): 502–508.
Published Online: 17 November 2021
...Serdar Kaya; Basak Kaya Objective: Preeclampsia, characterized by endothelial dysfunction, is associated with maternal and fetal Doppler alterations. This study aimed to evaluate fetal renal artery Doppler indices in pregnancies complicated with preeclampsia and compare them with normotensive...
Carlos José Molina Pérez, Ana Graciela Nolasco Leaños, Reyes Ismael Carrillo Juárez, María Guadalupe Berumen Lechuga, Irma Isordia Salas, Alfredo Leaños Miranda
Gynecol Obstet Invest (2021) 86 (5): 445–453.
Published Online: 18 October 2021
... to preeclampsia. Prediction of GH-related adverse outcomes is challenging because there are no available clinical tests that may predict their occurrence. Objective: The aim of the study was to determine the clinical usefulness of the soluble endoglin (sEng) and parameters of uterine artery flow (UtAF) measured...
Gynecol Obstet Invest (2021) 86 (3): 264–272.
Published Online: 17 June 2021
...Mi Cheng; Zequn Liu; Wanqing Ji; Jie Zheng; Huiqian Zeng; Fang Guo; Ping He Objectives: The pathogenesis of preeclampsia (PE) is associated with impaired trophoblast invasion, which results in placental insufficiency. Our earlier studies demonstrated that tissue transglutaminase (tTG) is highly...
Gynecol Obstet Invest (2021) 86 (3): 247–256.
Published Online: 09 June 2021
...Xiao-Lu Wang Objective: Determine the effect of interleukin (IL)-15 on HTR-8/SVneo cells and a preeclampsia (PE) mouse model induced by LPS. Methods: Transwell and Annexin-V-FITC/PI assays were performed in HTR-8/SVneo cells transfected with IL-15 activation plasmid/siRNA prior to LPS treatment...
Gynecol Obstet Invest (2020) 85 (4): 362–370.
Published Online: 21 September 2020
...Jianli Zhou; Dongfang Zhang; Jie Bai; Zhiguo Li; Yan Chen To investigate the expression of aquaporin 3 (AQP3) in placenta and fetal membranes and the level of adiponectin (ADP) in the umbilical cord blood of severe preeclampsia and to analyze the relationship between the 2 proteins and severe...
Carmen A.H. Severens-Rijvers, Salwan Al-Nasiry, Annemiek Vincken, Guido Haenen, Bjorn Winkens, Chahinda Ghossein-Doha, Marc A.E. Spaanderman, Louis L.H. Peeters
Gynecol Obstet Invest (2019) 84 (6): 616–622.
Published Online: 29 July 2019
..., instructions or products referred to in the content or advertisements. Preeclampsia Hypertension in pregnancy Pregnancy Antioxidants Trolox equivalent antioxidant capacity Uric acid Longitudinal Preeclampsia (PE) is a common placental syndrome (PS) and contributes importantly to maternal...
Jorge Valencia-Ortega, Arturo Zárate, Renata Saucedo, Marcelino Hernández-Valencia, José G. Cruz, Edgardo Puello
Gynecol Obstet Invest (2019) 84 (1): 12–19.
Published Online: 13 July 2018
... receptor antagonist (IL-1RA), intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1), along with the proinflammatory/anti-inflammatory cytokine ratios in women with preeclampsia (PE) vs. women with normal pregnancy (NP), and to analyze PE classified as early- (EO) and late-onset...
Agata Szpera-Gozdziewicz, Tomasz Gozdziewicz, Maciej Boruczkowski, Grzegorz Dworacki, Grzegorz H. Breborowicz
Gynecol Obstet Invest (2018) 83 (3): 252–258.
Published Online: 05 April 2018
... insight into the pathophysiology of pregnancy-related hypertension and show the potential method for disease prevention and therapy. Methods: We created 3 study groups: pregnant women with chronic hypertension ( n = 10), gestational hypertension ( n = 18), preeclampsia ( n = 21), and control (22 healthy...
Ping Zhang, Hailan Yang, Yongliang Feng, Weiwei Wu, Shuzhen Li, Brian Thompson, Bingjie Xie, Pengge Guo, Mei Li, Ying Wang, Nan Zhao, Suping Wang, Yawei Zhang
Gynecol Obstet Invest (2018) 83 (2): 179–186.
Published Online: 24 October 2017
... in preeclampsia (PE). The study aims to investigate whether single nucleotide polymorphisms (SNPs) in sex hormone-related genes are associated with PE. Method: We performed a nested case-control study including 436 pregnant women (203 PE and 233 healthy or normal pregnant women) to investigate associations...
Subject Area:Topic Article Package: Diabetes , Topic Article Package: Diabetes 2017 , Further Areas , Women's and Children's Health
Aya Mohr-Sasson, Eyal Schiff, Ramy Rahamim Suday, Zehava Hayman, Yeruham Kleinbaum, Anat Kalter-Farber, Roy Mashiach, Yoav Yinon, Moti Dulitzki, Eyal Sivan, Shali Mazaki-Tovi
Gynecol Obstet Invest (2017) 82 (5): 517–520.
Published Online: 19 May 2017
... patients with and without ultrasound findings in the rate of cholestasis of pregnancy, preeclampsia, chronic hypertension, and gestation diabetes. Conclusion: Abdominal ultrasound examination in this population has a low clinical yield. The decision to perform an abdominal ultrasound must be individualized...
Gynecol Obstet Invest (2016) 81 (6): 543–551.
Published Online: 21 October 2016
...Jing Li; Jun Zhou; Yuanhua Ye; Qunying Liu; Xiaojin Wang; Ning Zhang; Xietong Wang Background: Previous studies have shown that oxidative stress is an important factor in preeclampsia (PE). Heme oxygenase-1 (HO-1) and nuclear factor erythroid 2-related factor-2 (Nrf2) are protective proteins...
Subject Area:Topic Article Package: Pharmacology 2016 , Further Areas , Women's and Children's Health
Carmen A.H. Severens-Rijvers, Salwan Al-Nasiry, Chahinda Ghossein-Doha, Sara Marzano, Hugo Ten Cate, Bjorn Winkens, Marc A.E. Spaanderman, Louis L.H. Peeters
Gynecol Obstet Invest (2017) 82 (4): 355–360.
Published Online: 20 September 2016
... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Placental syndrome Preeclampsia Gestational hypertension PAI-2...
Gynecol Obstet Invest (2017) 82 (4): 388–397.
Published Online: 10 August 2016
...Weiping Chen; Yan Zhang; Chongyu Yue; Yuanhua Ye; Pingpin Chen; Wei Peng; Yufang Wang Objective: To investigate the expression of advanced glycation end products (AGEs) and the receptor for AGE (RAGEs) in maternal blood, umbilical blood and placental tissues in women with severe preeclampsia (sPE...
Gynecol Obstet Invest (2016) 81 (1): 28–33.
Published Online: 21 October 2015
... pre-eclampsia and normal pregnancies are shown in table 1 . Receptors C3a C5a Angiotensin II Antibodies Preeclampsia Pre-eclampsia, defined clinically by the de novo development of hypertension and proteinuria in pregnancy after 20 weeks of gestation, complicates 2-8% of all...
Gynecol Obstet Invest (2016) 81 (2): 137–147.
Published Online: 26 August 2015
...Hui-Qiang Liu; Yong-Hong Wang; Lan-Lan Wang; Min Hao Background: Preeclampsia (PE) is relatively common and is unpredictable in its onset and progression. Aims: We investigated the clinical value of using the multiple of the median (MoM) of free β-human chorionic gonadotropin (β-hCG) concentrations...
Gynecol Obstet Invest (2016) 81 (1): 78–83.
Published Online: 03 June 2015
...Enrique Valdés; Álvaro Sepúlveda-Martínez; Ana Tong; Magdalena Castro; Daniela Castro Background/Aims: Current evidence has tried to extrapolate the use of the protein:creatinine ratio (PCR) in a single urine sample as a rapid diagnostic tool for preeclampsia (PE). The present study addresses...
Gynecol Obstet Invest (2015) 80 (2): 99–105.
Published Online: 22 April 2015
... by intrauterine fetal growth restriction (IUGR) or preeclampsia (PE). Methods: This longitudinal, prospective, and case-controlled study was conducted over a period of 24 months. At-risk pregnancies involving small-for-gestational-age (SGA) fetuses, IUGR, gestational hypertension (GH), or PE were investigated...
Gynecol Obstet Invest (2015) 80 (3): 193–198.
Published Online: 17 April 2015
...Xuefeng Wang; Mengchun Liu; Zhen Liu; Zhaoyuan Niu; Shiguo Liu Objective: The purpose of our study was to investigate the association between polymorphism of rs2043211 in CARD8 and susceptibility to preeclampsia (PE) in the Chinese Han population. Methods: 261 PE patients and 451 controls were...