...Caihong Zhang; Zixi Chen; Huijing Shao; Ziwen Ma; Rui Guan; Xiaomin Yu; Qianqian Sun; Hang Gu Objectives: Necroptosis, a form of programmed cell death, can occur in the placenta of patients with preeclampsia (PE). Hydrogen sulfide (H 2 S) can inhibit necroptosis of human umbilical vein endothelial...

...Lidan He; Qiongfang Song; Jifen Hu; Jianbo Wu Objectives: Placental inflammation possibly underlies preeclampsia (PE) pathogenesis. This study aimed to investigate the expression of the high mobility box group 1 (HMGB1)-toll-like receptor 4 (TLR4) signalling pathway in preeclamptic placentas...

...Yubo Shi; Lianxiao Zhang; Linlin Wang; Huiqing Ding Objective: Preeclampsia (PE) is the most common gestational disease related to various biomolecules, including circular RNA. Hsa_circ_0088196 (circ_0088196) was aberrantly upregulated in PE tissues. Design: This study focused on the further...

...Serdar Kaya; Basak Kaya Objective: Preeclampsia, characterized by endothelial dysfunction, is associated with maternal and fetal Doppler alterations. This study aimed to evaluate fetal renal artery Doppler indices in pregnancies complicated with preeclampsia and compare them with normotensive...

... to preeclampsia. Prediction of GH-related adverse outcomes is challenging because there are no available clinical tests that may predict their occurrence. Objective: The aim of the study was to determine the clinical usefulness of the soluble endoglin (sEng) and parameters of uterine artery flow (UtAF) measured...

...Mi Cheng; Zequn Liu; Wanqing Ji; Jie Zheng; Huiqian Zeng; Fang Guo; Ping He Objectives: The pathogenesis of preeclampsia (PE) is associated with impaired trophoblast invasion, which results in placental insufficiency. Our earlier studies demonstrated that tissue transglutaminase (tTG) is highly...

...Xiao-Lu Wang Objective: Determine the effect of interleukin (IL)-15 on HTR-8/SVneo cells and a preeclampsia (PE) mouse model induced by LPS. Methods: Transwell and Annexin-V-FITC/PI assays were performed in HTR-8/SVneo cells transfected with IL-15 activation plasmid/siRNA prior to LPS treatment...

...Jianli Zhou; Dongfang Zhang; Jie Bai; Zhiguo Li; Yan Chen To investigate the expression of aquaporin 3 (AQP3) in placenta and fetal membranes and the level of adiponectin (ADP) in the umbilical cord blood of severe preeclampsia and to analyze the relationship between the 2 proteins and severe...

..., instructions or products referred to in the content or advertisements. Preeclampsia (PE) is a common placental syndrome (PS) and contributes importantly to maternal and perinatal morbidity and mortality worldwide. Its overall prevalence is about 4.6% [ 1 ] with a recurrence rate of about 25% [ 2 ]. Other...

... receptor antagonist (IL-1RA), intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 (VCAM-1), along with the proinflammatory/anti-inflammatory cytokine ratios in women with preeclampsia (PE) vs. women with normal pregnancy (NP), and to analyze PE classified as early- (EO) and late-onset...

... insight into the pathophysiology of pregnancy-related hypertension and show the potential method for disease prevention and therapy. Methods: We created 3 study groups: pregnant women with chronic hypertension ( n = 10), gestational hypertension ( n = 18), preeclampsia ( n = 21), and control (22 healthy...

... in preeclampsia (PE). The study aims to investigate whether single nucleotide polymorphisms (SNPs) in sex hormone-related genes are associated with PE. Method: We performed a nested case-control study including 436 pregnant women (203 PE and 233 healthy or normal pregnant women) to investigate associations...

... patients with and without ultrasound findings in the rate of cholestasis of pregnancy, preeclampsia, chronic hypertension, and gestation diabetes. Conclusion: Abdominal ultrasound examination in this population has a low clinical yield. The decision to perform an abdominal ultrasound must be individualized...

...Jing Li; Jun Zhou; Yuanhua Ye; Qunying Liu; Xiaojin Wang; Ning Zhang; Xietong Wang Background: Previous studies have shown that oxidative stress is an important factor in preeclampsia (PE). Heme oxygenase-1 (HO-1) and nuclear factor erythroid 2-related factor-2 (Nrf2) are protective proteins...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Placental syndrome Preeclampsia Gestational hypertension PAI-2...

...Weiping Chen; Yan Zhang; Chongyu Yue; Yuanhua Ye; Pingpin Chen; Wei Peng; Yufang Wang Objective: To investigate the expression of advanced glycation end products (AGEs) and the receptor for AGE (RAGEs) in maternal blood, umbilical blood and placental tissues in women with severe preeclampsia (sPE...

... to in the content or advertisements. Receptors C3a C5a Angiotensin II Antibodies Preeclampsia Pre-eclampsia, defined clinically by the de novo development of hypertension and proteinuria in pregnancy after 20 weeks of gestation, complicates 2-8% of all pregnancies [ 1 ]. Numerous theories have...

...Hui-Qiang Liu; Yong-Hong Wang; Lan-Lan Wang; Min Hao Background: Preeclampsia (PE) is relatively common and is unpredictable in its onset and progression. Aims: We investigated the clinical value of using the multiple of the median (MoM) of free β-human chorionic gonadotropin (β-hCG) concentrations...

...Enrique Valdés; Álvaro Sepúlveda-Martínez; Ana Tong; Magdalena Castro; Daniela Castro Background/Aims: Current evidence has tried to extrapolate the use of the protein:creatinine ratio (PCR) in a single urine sample as a rapid diagnostic tool for preeclampsia (PE). The present study addresses...

... by intrauterine fetal growth restriction (IUGR) or preeclampsia (PE). Methods: This longitudinal, prospective, and case-controlled study was conducted over a period of 24 months. At-risk pregnancies involving small-for-gestational-age (SGA) fetuses, IUGR, gestational hypertension (GH), or PE were investigated...