... polymorphisms with the risk of RM. Design: A combined meta-analysis was implemented in this study. Participants/Materials, Setting, Methods: Common electronic databases including PubMed, Embase, Web of Science, China National Knowledge Infrastructure, Cochrane Library, and Google Scholar were used to seek...

...Lingling Wu; Changping Fang; Jun Zhang; Yanchou Ye; Haiyan Zhao Objectives: Insulin receptor substrate 1 (IRS1) is a crucial factor in the insulin signaling pathway. IRS1 gene polymorphism rs1801278 in mothers has been reported to be associated with gestational diabetes mellitus (GDM). However...

... are influenced by many factors. Objective: The aim of this study was to investigate the relationship between plasma oxytocin and oxytocin receptor levels and oxytocin receptor polymorphisms in term and late-term pregnant women. Methods: Sixty-eight singleton pregnant women with late-term pregnancy and 83...

... in preeclampsia (PE). The study aims to investigate whether single nucleotide polymorphisms (SNPs) in sex hormone-related genes are associated with PE. Method: We performed a nested case-control study including 436 pregnant women (203 PE and 233 healthy or normal pregnant women) to investigate associations...

...Yali Du; Huifang Wang; Bei Lv Background: Several meta-analyses have been conducted to examine the possible link between X-ray repair cross-complementing groups 1 ( XRCC1 ) Arg399Gln polymorphism and cervical cancer risk. However, the results are controversial. Therefore, we carried out a more...

...Fang Zhang; Bing Li; Hong-Yan Wu; Li-Xin Shang Background: Many studies have examined the association of X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln polymorphism with cervical cancer susceptibility. However, the results of these studies are inconsistent. To further assess the effects...

.... Genotyping of XRCC1 codon 399 as well as of XRCC4 -1394T/G, codon 247 and intron 3 insertion/deletion variations was performed using restriction fragment length polymorphism analysis of PCR-amplified fragments. Results: The XRCC4 -1394TG genotype frequency was significantly lower (p = 0.005) in the patients...

...Chao Li; Binglong Qiao; Weihong Qi; Ying Zhan; Chunling Ma; Lei Zhao; Guiyu Li Objective: The purpose of the study was to investigate the association between macrophage migration inhibitory factor (MIF) gene polymorphisms and gestational diabetes mellitus (GDM) in Han Chinese women. Methods...

...Xuefeng Wang; Mengchun Liu; Zhen Liu; Zhaoyuan Niu; Shiguo Liu Objective: The purpose of our study was to investigate the association between polymorphism of rs2043211 in CARD8 and susceptibility to preeclampsia (PE) in the Chinese Han population. Methods: 261 PE patients and 451 controls were...

... polymorphisms on pregnancy outcomes among CMV-infected women. Methods: A total of 731 CMV-infected pregnant women (634 and 97 with normal and adverse pregnancy outcomes, respectively) were recruited. CMV load quantification and screening of TORCH coinfections were performed by using real-time polymerase chain...

... polymorphisms of pregnant women in Jiaodong region in China, and to investigate whether folic acid supplementation affect the pregnancy complications. Setting: A total of 7,812 pregnant women from the Jiaodong region in Shandong province in China. Methods: By using Taqman-MGB, 2,928 pregnant women (case group...

... in obstetric disorders. The aims of the present study were to investigate the effect of TNF-α gene G308A (rs1800629) polymorphism on disease risk, renal function, microvascular permeability, endothelial cell dysfunction and organ involvement in women with PE. Methods: Initially, 102 3rd-trimester pregnant...

...Dong Ock Lee; Hoon Kim; Seung-Yup Ku; Seok Hyun Kim; Jung Gu Kim Background/Aims: The purpose of this study was to investigate the association between single nucleotide polymorphisms (SNPs) in sclerostin (SOST), dickkopf (DKK), secreted frizzled-related protein (sFRP) genes and bone mineral density...

...Yunqin Chen; Dongguo Wang; Meiqian Zhou; Xiangjuan Chen; Jiayu Chen Background/Aims: The endothelial nitric oxide synthase (eNOS) gene has been enlisted by previous research as a candidate gene of preeclampsia predisposition. This study investigates the specific roles of 3 polymorphisms of the eNOS...

...Chao Li; Binglong Qiao; Ying Zhan; Wei Peng; Zi-Jiang Chen; Lirong Sun; Jingjing Zhang; Lei Zhao; Qun Gao Background/Aims: The purpose of this study was to investigate the association between MTNR1A and MTNR1B gene polymorphisms and gestational diabetes mellitus (GDM) in Han Chinese women. Methods...

... contains common genetic polymorphisms that influence gene activity. Clinical implications of TP53 polymorphisms have been reported for several diseases, including a variety of solid tumors and endometriosis. We evaluated the association of a TP53 duplication polymorphism with endometriosis. Methods: We...

... was to determine whether or not the MTNR1A gene polymorphism is associated with a predisposition to PCOS. Methods: The single nucleotide polymorphism (SNP) rs2119882 in the MTNR1A gene was detected in 482 patients with PCOS and 522 healthy Chinese Han women. Subsequently, the association of MTNR1A gene variants...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Uterine leiomyoma X-Inactivation Differential methylation Clonality Polymorphism Phosphoglycerokinase Original Paper Gynecol Obstet Invest...

...Soo Jin Chae; Gyoung Hoon Lee; Young Min Choi; Min A Hong; Jong Mee Kim; Kyu Sup Lee; Seung Yup Ku; Shin Yong Moon Background/Aims: The aim of this study was to investigate the possibility that the K469E and G241R polymorphisms in the intercellular adhesion molecule-1 (ICAM-1) gene and the C-634G...

... Microarray Color Doppler Polymorphism Pre-eclampsia Original Article Gynecol Obstet Invest 2009;68:239 247 DOI: 10.1159/000238381 Received: October 27, 2008 Accepted after revision: April 18, 2009 Published online: September 17, 2009 Analysis of Nitric Oxide Metabolism as a Placental or Maternal Factor...