... are influenced by many factors. Objective: The aim of this study was to investigate the relationship between plasma oxytocin and oxytocin receptor levels and oxytocin receptor polymorphisms in term and late-term pregnant women. Methods: Sixty-eight singleton pregnant women with late-term pregnancy and 83...

...Nezahat Öztürk Akay; Deniz Hızlı; Saynur Sarıcı Yılmaz; Serdar Yalvaç; Ömer Kandemir Aims: The aim of this study was to compare the efficacy of oxytocin and dinoprostone in achieving successful labor induction and vaginal delivery in postterm women with an unfavorable cervix. Methods: Postterm...

...Kemal Güngördük; Gokhan Yildirim; Ozgu Güngördük; Cemal Ark; İsmet Tekirdağ Objective: To compare the efficacy and safety of sustained-release dinoprostone vaginal pessary and concurrent high-dose oxytocin infusion with sustained-release dinoprostone vaginal pessary followed 6 h later by high-dose...

...Y. Ogawa; L. Herod; J.T. Lanman A soya bean oil containing predominantly phospholipids (SBP) has been known to sensitize the pregnant rabbit uterus to oxytocin, permitting premature induction of labor. We are attempting to identify the active component. Lipid class analyses of SBP revealed...

...Mary E. Carsten Purified preparations of fragmented sarcoplasmic reticulum from non-pregnant bovine uterus bind calcium from a medium containing ATP and Mg ++ . This calcium binding was enhanced in the presence of progesterone, while it is decreased in the presence of oxytocin. In the presence...

.... The fallopian tube remains active during gestation in contrast with the uterus which is quiescent. The early puerperal tube displays a pattern of activity similar to that recorded during the late luteal phase of the menstrual cycle. Activation occurs during suckling and in response to exogenous oxytocin...

...Joseph Seitchik; Marvin L. Chatkoff A retrospective study was designed to contrast the intrauterine pressure wave form characteristics of hypocontractile labor in patients with and without obstruction and before and after oxytocin therapy. No differences were observed between the patient groups...

...James L. Warr; Luis A. Branda Phospholipase C ( Clostridium welchii and Bacillus cereus ) treatment of lactating rabbit mammary gland membranes (140,000 g pellet and sucrose density gradient purified plasma membranes) resulted in a large decrease in the binding of [ 3 H]oxytocin...

...D.J. Crankshaw; E. Romaniuk; L.A. Branda Receptors for oxytocin were identified in a particulate fraction from the myometrium of the pregnant ewe. Specific binding of [ 3 H]-oxytocin was rapid, reversible, and saturable. It showed an absolute requirement for Mg 2+ and the selectivity among oxytocin...

... on myometrial strips obtained during active, spontaneous labor. Both PGE 2 and PGF 2Α had a marked stimulatory effect on strips from the upper uterine segment. The lower segment reacted to PGE 2 by inhibition but not at all or slightly stimulatory to PGF 2Α Oxytocin constantly induced an excitatory response...

...W. Lichtenegger; M. Lahousen; H. Kraemer 153 oral prostaglandin E 2 (PGE 2 ) inductions of labour were compared with 172 inductions with oxytocin. Details of these inductions are presented. After review of the data we assumed that induction of labour with oral PGE 2 is less hazardous to mother...

...L. Vankrieken; A. Godart; K. Thomas A sensitive and specific radioimmunoassay method was developed for the determination of oxytocin in human serum. Serum oxytocin levels were assayed in five healthy male volunteers and four healthy non pregnant female volunteers after rapid intravenous injection...

... activity was determined in the incubation medium by measurement of the hydrolytic activity against the synthetic peptide 2,4-dinitrophenyl-Pro-Gln-Gly-Ile-Ala-Gly-Gln- D -Arg-OH. Stimulated collagenolytic activity was seen in the presence of relaxin and oxytocin whereas prostaglandin E 2 , prostaglandin F...

...Andrea R. Genazzani; Felice Petraglia; Fabio Facchinetti; Paolo A. Galli; Annibale Volpe Β-Endorphin (Β-EP), Β-lipotropin (Β-LPH) and cortisol plasma levels were measured during labor in 18 pregnant women. In 7 cases labor progressed spontaneously and in 11 cases oxytocin (5 mlU/min...

...G. Rydén; R.G.G. Andersson; G. Berg; S.-G. Karlsson; Y. Oscarsson The binding of 3 H-oxytocin ( 3 H-OT) and 3 H-arginine-vasopressin ( 3 H-AVP) and the displacement from binding sites by four oxytocin analogues were studied in myometrial membrane preparations from full-term pregnant women. Specific...

...Marjan Pajntar; Drago Rudel The electrical activity of the cervix can be measured during labour. The influence of oxytocin on electromyographic (EMG) activity of the cervical musculature was studied in 80 primiparous women after induction of labor. The highest electrical activity registered...

...Tatsuhiko Kawarabayashi; Yutaka Narisawa; Kayoko Nakamura; Hajime Sugimori; Masao Oda; Yoshio Taniguchi A case of an allergic reaction to synthetic oxytocin administered during cesarean section is reported. Epinephrine was more effective in improving the severe hypotension than ephedrine...

...Ioannis Papageorgiou; Christina Tsionou; Demetrios Minaretzis; Stylianos Michalas; Dionysios Aravantinos Labor characteristics after intracervical application of 0.5 mg prostaglandin (PG) E 2 gel (n = 83) versus intravenous administration of oxytocin (n = 82) for labor induction were investigated...

...Douglass Crall; Donald R. Mattison Despite common use in obstetrics for almost 50 years, there is still disagreement concerning optimal clinical protocols for the use of oxytocin. This disagreement arises in part from inadequate data on oxytocin phar-macokinetics and pharmacodynamics. This report...

... by radioimmunoassay during spontaneous labor and labor induced by oxytocin (OT), prostaglandin F 2Α (PGF 2Α ), or PGE 2 (PGE 2 ). Subjects were 7 Japanese women in each labor group. Plasma cAMP levels significantly rose at the time of crowning of the fetal head in all 4 groups. They did not increase until that time...