...Xinyue Liu; Li Guo; Yuping Suo; XinHui Tang; Ting Zhu; Tiannan Zhao; Weina Zhang; Ping Zhang Objectives: This study aimed to investigate the involvement of the cell cycle-related protein centromere protein F (CENPF) in the development of ovarian cancer (OC) and explored its relationship...

...Cheng Chen; Ying Zhu; Haibo Zhang; Lan Xiao Introduction: DNA methylation plays an important role in the carcinogenesis, progression, and prognosis of various human cancers. RASSF1A, BRCA1, APC, and p16 are the frequently methylated genes among patients with ovarian cancer. Therefore, our study...

...Meiqiong Li; Jiaye Long; Miyang Yang; Yingrong Pang; Baoxiang Chen; Hong Li Introduction: The link between cruciferous vegetables (CVs) and ovarian cancer (OC) is still uncertain. This meta-analysis is intended to investigate the association between CV consumption and the risk of OC, as well...

...Jing Zou; Long Jian Objective: Chemoresistance in ovarian cancer results in treatment failure, yet underlying mechanisms that regulate chemoresistance remain largely unclear. There is emerging evidence relating ovarian cancer drug resistance with bioactive sphingolipids and regulation...

...Bo Rim Kim; Heewon Kim; Se-gyeong Joo; Eun Jin Jang; Junwoo Jo; Hannah Lee; Ho Geol Ryu Objectives: The goal of ovarian cancer surgery has recently shifted from optimal cytoreduction to more complete resection. This study attempted to reassess and update the association between surgical case-volume...

... mapping is the cervix. However, in apparent early-stage ovarian cancer, current trials map the pelvic area injecting the tracers in the utero-ovarian ligament. A different injection site is proposed based on a possible different lymphatic ovarian drainage through the utero-ovarian ligament and uterus...

...Man Liang; Qin Li; Shuai Shi; Ya-ning Tian; Yanhong Feng; Yongkang Yang; Miao Dong; Jing Zhang; Jihong He Background: Ovarian cancer, one of the most malignant diseases in female, is associated with poor diagnosis and low 5-year survival rate. Taxol is a widely used chemotherapeutic drug...

... significantly increased contractions in the ovarian cancer group (both p < 0.001). Limitations: These results require now to be placed into a firm clinical context. Conclusions: Our study indicates that ovarian cancer considerably alters contractile activity of the nonpregnant human uterus in response...

... in tumorigenic progression of ovarian cancer. However, the effects of miR-301a on ovarian cancer are still unclear. Objective: The objective of this study is to investigate the molecular mechanisms of miR-301a in epithelial ovarian cancer cells. Methods: The miR-301a expression in ovarian cancer cells...

..., risk of recurrence and alternative options . Hum Reprod Update . 2013 ; 19 ( 2 ): 151 – 66 . 3. Vernooij   F , Heintz   P , Witteveen   E , van der Graaf   Y . The outcomes of ovarian cancer treatment are better when provided by gynecologic oncologists and in specialized...

...Yinlong Zhao; Shirui Liu; Yu Wen; Lili Zhong Objective: The objective of this study is to explore the role of miR-210 in the growth of ovarian cancer cells and the correlation with radiotherapy and to elucidate underlying molecular mechanisms. Methods: Human ovarian cancer cell lines OVCAR3...

...Haitham A. Torky; Ahmed Sherif; Ashraf Abo-Louz; Mohamed Ali; Ali Ahmed; Ahmad Ali Introduction: Ovarian cancer is a relatively common occurrence with the formation of a tumour in the ovaries and is the leading cause of death in the gynecological field. Despite enormous efforts...

... expression Ovarian cancer Intracellular localization Although ovarian cancer (OC) ranks eighth among the most common female malignancies, it is the fifth cause of death due to cancer in women [ 1 ]. This discrepancy is largely attributed to the fact that the majority of patients present...

... between the fallopian tube and ovary will lead to decreased ovarian function and the premature onset of menopause [ 10 ], even though salpingectomy stands to benefit a substantial number of women as a risk-reduction strategy to prevent the development of ovarian cancer. However, there have been no studies...

...Liangliang Wang; Lihua Wang; Ling Ma; Jingbo Liu; Shanshan Ma Background: The overall survival rate of ovarian cancer patients is still poor because of the difficulties encountered in detection, diagnosis and treatment. Here, we aim to systematically identify the genetic factors causing ovarian...

...Jun Ou-Yang; Li-Hong Huang; Xiang-Xiu Sun Objective: The study aimed to investigate cyclin-dependent kinase 14 (CDK14) and its co-function with Wnt signaling pathway on cell proliferation, migration and invasion in ovarian cancer. Methods: CDK14 expressions were detected by quantitative real-time...

... ultrasonography (US) score in predicting ovarian cancer (OC) in women who present with pelvic or adnexal masses. Methods: Pelvic US, serum CA125 and HE4 levels were investigated preoperatively in consecutively enrolled Thai women over 18 years with clinically diagnosed pelvic or adnexal masses who were undergoing...

... cancer Recurrence In 2014, it was estimated that over 21,000 women will be diagnosed with ovarian cancer and over 14,000 women will die from the disease [ 1 ]. While not the most common type of gynecologic cancer diagnosed in the United States, ovarian cancer is the most fatal. The majority...

...Jun Liang; Bo Yang; Qinying Cao; Xiaohua Wu Aims: This study was conducted to investigate the association of vasculogenic mimicry (VM) formation and CD133 expression with the clinical outcomes of patients with ovarian cancer. Methods: This retrospective study was performed in 120 ovarian carcinoma...

...Tingting Zhao; Weiping Hu Aims: This study aimed to examine the clinical significance of carbohydrate antigen 125 (CA125) and human epididymis protein 4 (HE4) serum levels in combination for ovarian cancer detection in patients. Methods: In total, 75 patients with ovarian cancer, 86 patients...