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1-20 of 51
Keywords: Immunohistochemistry
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Journal Articles
Silent Information Regulator 1 Promotes Proliferation, Migration, and Invasion of Cervical Cancer Cells and Is Upregulated by Human Papillomavirus 16 E7 Oncoprotein
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Gynecol Obstet Invest (2022) 87 (1): 22–29.
Published Online: 22 November 2021
...: Immunohistochemistry results revealed that the expression of SIRT1 was upregulated with progression from CIN II–III to CC, but was not expressed in normal cervical tissues and CIN I. There was a positive correlation between SIRT1 expression and HPV16 E7 expression in CC tissues, and silencing of HPV16 E7 downregulated...
Journal Articles
Expression of the Peptidase “Fibroblast Activation Protein” on Decidual Stromal Cells Facilitating Tissue Remodeling
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Gynecol Obstet Invest (2020) 85 (5): 428–436.
Published Online: 10 November 2020
... pregnancy. Methods/Results: The expression of FAP was analyzed by immunohistochemistry in frozen sections of decidual tissue from early pregnancy (gestational weeks: 6–12). All tissue samples clearly displayed a strong expression of FAP on the surface of stromal fibroblasts. Additionally, the percentage...
Journal Articles
The Significance of Galectin-1 and Galectin-9 Expression in Endometrial Carcinoma
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Gynecol Obstet Invest (2020) 85 (1): 34–40.
Published Online: 05 September 2019
...Xiao-fei Sun; Shu-yan Dai Objectives: To explore the expression of Galectin-1 and -9 and clinicopathological features in endometrial carcinoma (EC). Methods: Normal endometrium (NE), atypical endometrial hyperplasia (AH), and endometrial cancer were collected, and immunohistochemistry was used...
Journal Articles
Role of Alpha-Smooth Muscle Actin and Fibroblast Activation Protein Alpha in Ovarian Neoplasms
Available to PurchaseAna Carolinne da Silva, Millena Prata Jammal, Renata Margarida Etchebehere, Eddie Fernando Candido Murta, Rosekeila Simões Nomelini
Gynecol Obstet Invest (2018) 83 (4): 381–387.
Published Online: 05 April 2018
...) in the stromal microenvironment of benign and malignant ovarian epithelial neoplasms, and to relate their tissue expression with prognostic factors in ovarian cancer. Methods: α-SMA and FAP were evaluated by immunohistochemistry in malignant ( n = 28) and benign ( n = 28) ovarian neoplasms. Fisher’s exact test...
Journal Articles
Serous Carcinoma of the Uterine Cervix, an Extremely Rare Aggressive Entity: A Literature Review
Available to PurchaseJoanna Jonska-Gmyrek, Agnieszka Zolciak-Siwinska, Leszek Gmyrek, Wojciech Michalski, Grazyna Poniatowska, Malgorzata Fuksiewicz, Pawel Wiechno, Jakub Kucharz, Maria Kowalska, Beata Kotowicz
Gynecol Obstet Invest (2018) 83 (3): 220–226.
Published Online: 23 January 2018
... cytoplasm, leading to scalloped configuration [ 3 ]. Immunohistochemistry is extremely helpful in diagnosis and the differential procedures in this rare entity [ 17 ]. Negativity for WT-1 (Wilms tumour factor) may be helpful in differentiation between USCC and ovarian cancer [ 13 ]. The strong, diffuse...
Journal Articles
Stromal Growth Differentiation Factor 15 and Its Association with Ovarian Cancer
Available to PurchaseCid A. Lima, Millena P. Jammal, Agrimaldo Martins-Filho, Thales Parenti Silveira, Douglas C. Micheli, Beatriz M. Tavares-Murta, Eddie F.C. Murta, Rosekeila Simões Nomelini
Gynecol Obstet Invest (2018) 83 (1): 35–39.
Published Online: 12 May 2017
... was histopathological diagnosis of ovarian epithelial neoplasia. Exclusion criteria were secondary malignant ovarian neoplasia and preoperative treatment. Serum and tissue levels of GDF-15 were assessed by enzyme-linked immunosorbent assay and immunohistochemistry, respectively. Chi-square test and unpaired t test were...
Journal Articles
Investigation of New Therapeutic Targets in Undifferentiated Endometrial Sarcoma
Available to PurchaseMin-Hyun Baek, Jeong-Yeol Park, Chae Chun Rhim, Jong-Hyeok Kim, Yangsoon Park, Kyu-Rae Kim, Joo-Hyun Nam
Gynecol Obstet Invest (2017) 82 (4): 329–339.
Published Online: 27 January 2017
... endometrial sarcoma Target therapy Immunohistochemistry Table 3 indicates the differences in survival outcome by treatment type and expression of therapeutic targets in the current study patients with UES. The immunoreactivity of each biomarker was different. In some cases, there was almost...
Journal Articles
Association of Vasculogenic Mimicry Formation and CD133 Expression with Poor Prognosis in Ovarian Cancer
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Gynecol Obstet Invest (2016) 81 (6): 529–536.
Published Online: 29 April 2016
... Prognosis Immunohistochemistry Based on patients' clinical and pathological characteristics, the results of immunohistochemical staining for identification of VM and CD133 expression were organized and summarized in table 2 . Both VM formation and CD133 expression were associated with tumor...
Journal Articles
Laparoscopic Management of Sclerosing Stromal Tumors of the Ovary Combined with Ectopic Pregnancy
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Gynecol Obstet Invest (2015) 80 (4): 276–280.
Published Online: 08 July 2015
.../l), and culdocentesis yielded 4 ml pale bloody fluid. Laparoscopy Ectopic pregnancy Pregnancy outcome Sclerosing stromal tumor of the ovary Immunohistochemistry An SSTO is a rare tumor, and little is known about its tissue origin, etiology, and pathogenesis. Sex cord stromal tumors...
Journal Articles
Aberrant Immunoreactivity of Deoxyribonucleic Acid Methyltransferases in Adenomyosis
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Gynecol Obstet Invest (2012) 74 (2): 100–108.
Published Online: 04 May 2012
... methyltransferases Dysmenorrhea, severity Epigenetics Menorrhagia Immunohistochemistry Adenomyosis is a common gynecologic disorder with a poorly understood pathogenesis [ 1 ]. Presented with a soft and diffusely enlarged uterus, patients with adenomyosis often complain of menorrhagia, dysmenorrhea...
Journal Articles
Elevated Immunoreactivity against Class I Histone Deacetylases in Adenomyosis
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Gynecol Obstet Invest (2012) 74 (1): 50–55.
Published Online: 26 April 2012
... stained for 3–5 min or until appropriate for microscopic examination with diaminobenzidine and then counterstained with hematoxylin (30 s) and mounted. A negative control was also incorporated using pre-immune IgG instead of the primary antibody. The protocol for immunohistochemistry analysis...
Journal Articles
Alpha-1-Antitrypsin Acts as a Preeclampsia-Related Protein: A Proteomic Study
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Gynecol Obstet Invest (2012) 73 (3): 252–259.
Published Online: 08 March 2012
... severe preeclampsia (LS-PE; n = 10 per group). Real-time quantitative PCR and immunohistochemistry were conducted to confirm the expression of α 1 -antitrypsin (α 1 -AT) in the decidual tissues of different subjects. ELISA was employed to detect the α 1 -AT content in the peripheral blood of 90 women (n...
Journal Articles
Phenotypic Characterisation of the Inner and Outer Myometrium in Normal and Adenomyotic Uteri
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Gynecol Obstet Invest (2011) 71 (4): 217–224.
Published Online: 15 December 2010
... in a university department. Morphometric features of the myometrium were studied in uteri from pre- and postmenopausal women with and without uterine adenomyosis as the sole pathology. Uteri were also divided according to the phase of the cycle and examined using immunohistochemistry and image analysis. Results...
Journal Articles
Placental Proteins in Peripheral Blood and Tissues of Ectopic Pregnancies
Available to PurchaseDitte Tornehave, John Chemnitz, Jes G. Westergaard, Børge Teisner, Henning K. Poulsen, Anthony E. Bolton, Jurgis G. Grudzinskas
Gynecol Obstet Invest (1987) 23 (2): 97–102.
Published Online: 15 March 2010
... to in the content or advertisements. Placental proteins Immunohistochemistry Human chorionic gonadotrophin Schwangerschaftsprotein 1 Pregnancy-associated plasma protein A Ectopic pregnancies Gynecol, obstet. Invest. 23: 97-102 (1987) © 1987 S. Karger AG. Basel 0378-7346/87/0232-009752.75/0 Placental...
Journal Articles
Expression of CA 125 in Adenomyosis (With 1 color plate)
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Gynecol Obstet Invest (1987) 23 (2): 122–123.
Published Online: 15 March 2010
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. CA 125 Adenomyosis Immunohistochemistry Short Communications Gynecol, obstct. Invest. 23: 122-123 (1987) © 1987 S...
Journal Articles
Basement Membranes in Progressing Intraepithelial Cervical Neoplasia: An Ultrastructural and Immunohistochemical Study with Antibodies against Human Type IV Collagen and Laminin
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Gynecol Obstet Invest (1985) 20 (3): 158–166.
Published Online: 15 March 2010
... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Cervix Cancer, cervical Immunohistochemistry Laminin Collagen IV Gynecol, obstet. Invest. 20: 158-166 (1985) © 1985 S. Karger AG. Basel 0378-7346/85/0203-0158S2.75/0 Basement...
Journal Articles
Localization of 15-Hydroxy Prostaglandin Dehydrogenase in Human Fetal Membranes, Decidua, and Placenta during Pregnancy
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Gynecol Obstet Invest (1992) 33 (3): 142–146.
Published Online: 15 March 2010
... was localized by immunohistochemistry to syncytiotrophoblast, cytotrophoblast, and intermediate trophoblast of placenta. At 23–30 weeks of gestation and at term IR-PGDH was present in syncytiotrophoblast and intermediate trophoblast, but not in cytotrophoblast in placenta. It was absent from amnion...
Journal Articles
Innervation of the Human Uterine Artery and Contractile Responses to Neuropeptides
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Gynecol Obstet Invest (1991) 31 (1): 30–36.
Published Online: 02 March 2010
..., Sweden Key Words. Uterine artery Neutrotransmitters Neuropeptides Immunohistochemistry Contractile effects Abstract. The intrinsic innervation of the human uterine artery was investigated histochemically, and the motor responses to some of the demonstrated peptides and other humoral factors were...
Journal Articles
Bilateral Gonadoblastoma Producing Steroid Hormones in a Patient with 45, X/46, XY Gonadal Dysgenesis
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Gynecol Obstet Invest (1990) 30 (3): 189–191.
Published Online: 02 March 2010
... female Gonadoblastoma Immunohistochemistry Steroidogenesis Gynecol Obstet Invest 1990;30:189-191 © 1990 S. Karger AG, Basel 0378-7346/90/0303-0189S2.75/0 Bilateral Gonadoblastoma Producing Steroid Hormones in a Patient with 45,X/46,XY Gonadal Dysgenesis Yoshihito Fukamatsu, Yoshiharu Tsukahara...
Journal Articles
Immunohistochemical Localization of Blood Group Substances in Normal and Neoplastic Endometrial Tissues – With Special Reference to Type 1 Core Chain Expression
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Gynecol Obstet Invest (1991) 32 (3): 185–188.
Published Online: 02 March 2010
... indicated that type 1 core chains were newly synthesized according to malignant transformations in endometrial tissues and they were partially fucosylated and partially sialylated. Type 1 chain Precursor Immunohistochemistry Endometrium Endometrial carcinoma Blood group antigen Gynecol Obstet...
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