Background: Spontaneous rupture of the uterus is a life-threatening obstetric complication in rare cases associated with previously performed salpingectomy. Aim: This paper presents an analysis of uterine rupture cases during pregnancy in patients after surgical removal of the fallopian tubes. Methods: The English and Polish language literature was reviewed for studies published between January 1, 1980 and September 30, 2014 to identify articles that described rupture of the uterus in women with a previous history of salpingectomy. Results: Thirteen case reports and case series studies in 18 women were identified. 33% of cases of uterine rupture following salpingectomy occurred during intrauterine pregnancy, whereas the rest was associated with interstitial ectopic pregnancy. Laparoscopic salpingectomy more often resulted in rupture of the uterus during non-ectopic pregnancy as compared to laparotomy (4 vs. 2 cases, respectively). When interstitial pregnancies were excluded, uterine rupture was a cause of fetal death in 67% of reported gestations. There were no cases of maternal mortality. Conservative treatment was the preferred management option, and total hysterectomy was performed in only 2 patients. Conclusion: Particular attention should be paid to patients with a previous history of salpingectomy due to the risk of uterine rupture throughout the entire pregnancy.

Ofir K, Sheiner E, Levy A, Katz M, Mazor M: Uterine rupture: risk factors and pregnancy outcome. Am J Obstet Gynecol 2003;189:1042-1046.
Ronel D, Wiznitzer A, Sergienko R, Zlotnik A, Sheiner E: Trends, risk factors and pregnancy outcome in women with uterine rupture. Arch Gynecol Obstet 2012;285:317-321.
Kaczmarczyk M, Sparén P, Terry P, Cnattingius S: Risk factors for uterine rupture and neonatal consequences of uterine rupture: a population-based study of successive pregnancies in Sweden. BJOG 2007;114:1208-1214.
Claeys J, Hellendoorn I, Hamerlynck T, Bosteels J, Weyers S: The risk of uterine rupture after myomectomy: a systematic review of the literature and meta-analysis. Gynecol Surg 2014;11:197-206.
Olobo-Lalobo JH: A hole in a primigravid uterus - an unusual finding at elective caesarean section. Postgrad Med J 1984;60:559-560.
Kasprowicz M, Olbryś T: Spontaneous rupture of the pregnant uterus in a primipara as an unusual complication of previous salpingectomy. Ginekol Pol 1996;67:520-521.
Inovay J, Marton T, Urbancsek J, Kadar Z, Altdorfer K, Papp Z: Spontaneous bilateral cornual uterine dehiscence early in the second trimester after laparoscopic salpingectomy and in-vitro fertilization. Hum Reprod 1999;14:2471-2473.
Ayoubi JM, Fanchin R, Lesourd F, Parant O, Reme JM, Monrozies X: Rupture of a uterine horn after laparoscopic salpingectomy. J Reprod Med 2003;48:290-292.
Chatterjee J, Abdullah A, Sanusi FA, Irvine L, Griffin D: A rare sequel following cornual ectopic pregnancy: a case report. BMJ Case Rep DOI: 10.1136/bcr.02.2009.1614.
Muglu J, Uchil D, Sau A, Zamblera D, Jolaoso A: Recurrent uterine rupture after laparoscopic surgery for interstitial ectopic pregnancy. J Gynecol Surg 2012;28:169-171.
Iuchtman M, Grunstein S: Acute abdomen in ruptured interstitial pregnancy following unilateral salpingectomy. Eur J Obstet Gynecol Reprod Biol 1987;26:165-168.
Dumesic DA, Damario MA, Session DR: Interstitial heterotopic pregnancy in a woman conceiving by in vitro fertilization after bilateral salpingectomy. Mayo Clin Proc 2001;76:90-92.
Arbab E, Boulieu D, Bied V, Payan F, Lornage J, Guérin JE: Uterine rupture in first or second trimester of pregnancy after in-vitro fertilization and embryo transfer. Hum Reprod 1996;11:1120-1122.
Su MT, Hsu KF, Kuo PL: Delayed uterine rupture after fetal reduction in a case of cornual heterotopic pregnancy. Taiwan J Obstet Gynecol 2005;44:270-272.
Banaszczyk R, Radwan J, Wójcik D, Radwan M: Uterine rupture in the second trimester of pregnancy after in-vitro fertilization and embryo transfer - case report. Adv Clin Exp Med 2005;14:1121-1124.
Pluchino N, Ninni F, Angioni S, Carmignani A, Genazzani AR, Cela V: Spontaneous cornual pregnancy after homolateral salpingectomy for an earlier tubal pregnancy: a case report and literature review. J Minim Invasive Gynecol 2009;16:208-211.
Galati GM, Santomarco N, Tarquini M, Caramazza D, Tiralongo GM, Boninfante M: Spontaneous uterine rupture during cornual ectopic pregnancy after recent homolateral salpingectomy. It J Gynaecol Obstet 2013;25:72-75.
Medel JM, Mateo SC, Conde CR, Cabistany Esqué AC, Ríos Mitchell MJ: Spontaneous uterine rupture caused by placenta percreta at 18 weeks' gestation after in vitro fertilization. J Obstet Gynaecol Res 2010;36:170-173.
Fylstra DL: Ectopic pregnancy not within the (distal) fallopian tube: etiology, diagnosis, and treatment. Am J Obstet Gynecol 2012;206:289-299.
Agdi M, Tulandi T: Surgical treatment of ectopic pregnancy. Best Pract Res Clin Obstet Gynaecol 2009;23:519-527.
Ng S, Hamontri S, Chua I, Chern B, Siow A: Laparoscopic management of 53 cases of cornual ectopic pregnancies. Fertil Steril 2009;92:448-452.
Hajenius PJ, Engelsbel S, Mol BW, Van der Veen F, Ankum WM, Bossuyt PM, Hemrika DJ, Lammes FB: Randomised trial of systemic methotrexate versus laparoscopic salpingostomy in tubal pregnancy. Lancet 1997;350:774-779.
Bouyer J, Coste J, Fernandez H, Pouly JL, Job-Spira N: Sites of ectopic pregnancy: a 10 year population-based study of 1800 cases. Hum Reprod 2002;17:3224-3230.
Hwang JH, Lee JK, Lee NW, Lee KW: Open cornual resection versus laparoscopic cornual resection in patients with interstitial ectopic pregnancies. Eur J Obstet Gynecol Reprod Biol 2011;156:78-82.
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