The management of cervical intraepithelial neoplasia (CIN2–3) diagnosed during pregnancy was the subject of this study. Two hundred and eight pregnant women with an abnormal cytology were assessed in our unit over a 10-year period. The age of the patients ranged from 20 to 45 (mean 28) years. Seventy-eight of these women were histologically proven to have CIN2–3. All patients were followed up every 8–10 weeks by cytology and colposcopy during pregnancy and reassessed 8–12 weeks postpartum. The disease persisted in 30 cases (38.4%), whereas in the remaining 48 cases it regressed to CIN1. No case of invasive disease developed during the follow-up period in these pregnant patients. Conservative management of CIN2–3 during pregnancy is acceptable, but close follow-up and colposcopic expertise are necessary.

Keywords:
CIN2–3, pregnancy, Colposcopy, Conservative treatment, CIN2–3
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© 2002 S. Karger AG, Basel
2003
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