528 women with either a dysplastic or a neoplastic change in the squamous epithelium of the uterine cervix were histologically assessed with special emphasis on the detection of the newly discovered condylomatous lesions (flat, inverted and papillomatous). A total of 289 condylomatous (CO) lesions were found, the flat being most frequent (78.9%) followed by the inverted (14.5%) and the papillomatous ones (6.6%). The mean age (31.8 years) of the women with CO lesions was significantly lower (p < 0.0001) than that of their non-condylomatous (N-CO) counterparts (43.0 years). The classical papillomatous condyloma was characterized as a lesion of the youngest age groups and associated with mild dysplasias, while the other two condyloma types were found in somewhat older women and frequently associated with more severe epithelial atypias (the severe dysplasias, in situ and invasive carcinomas). The possible role of human papilloma virus, the etiologic agent of the condylomas, as an agent responsible for or contributing to the development of the squamous cell carcinoma of the uterine cervix was discussed in the light of the present findings. The conclusion was drawn that this possibility should be seriously considered.

Keywords:
Condylomas, Human papilloma virus, Epithelial dysplasias, Cervical carcinoma, Human oncogenesis
This content is only available via PDF.
© 1980 S. Karger AG, Basel
1980
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.