Fragestellung: Der Einfluss einer oralen Tokolyse (Fenoterol 40 mg/Tag) auf die Glukose-, Insulin- und C-Peptid-Kinetik während eines oralen Glukosetoleranztestes (oGTT) mit 100 g Glukose (Hexokinasemethode, Kriterien nach Sacks) wurde im dritten Trimenon untersucht. Methoden: 54 Patientinnen ohne Tokolyse, davon 25 mit pathologischem oGTT, und 36 Patientinnen mit Tokolyse, davon 18 mit pathologischem oGTT, wurden vergleichend analy-siert. Ergebnisse: Sowohl die Patientinnen mit normalem als auch die Patientinnen mit pathologischem oGTT zeigten keinen konstanten signifíkanten Unterschied hinsichtlich der Glukose-, Insulin- und C-Peptid-Konzentrationen bei einem Vergleich der Schwangeren mit und ohne Tokolyse. Unter Tokolyse kam es zu einem frühzeitigeren Anstieg des Insulins. Auch bestand eine Tendenz zu höheren Werten für C-Peptid und niedrigeren Werten für den C-Peptid/Insulin-Quotienten.

Keywords:
Tocolysis, Glucose, Insulin, C-peptide, Gestational diabetes
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© 1995 S. Karger AG, Basel
1995
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