Kann die Trophoblastpersistenz nach tubenerhaltender, operativer Therapie der Extrauteringravidität mittels systemischer Methotrexatmedikation erfolgreich behandelt werden? Wir berichten über eine Patientin mit Trophoblastpersistenz und diskutieren die bisher publizierte Literatur dazu. Mittels systemischer Methotrexattherapie kann eine für die Patientin vom chirurgischen, anästhesiologischen und psychologischen Standpunkt her belastende Reoperation im beschriebenen Fall wie auch in der überwiegenden Mehrzahl der publizierten Fälle vermieden werden. Aufgrund der vorliegenden Zahlen kann die Methotrexattherapie bei der Trophoblastpersistenz als einfache, effíziente, erfolgreiche und inzwischen etablierte Therapie betrachtet werden.

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