...Taihao Quan; Gary J. Fisher Human skin is largely composed of a collagen-rich connective tissue, which provides structural and functional support. The collagen-rich connective tissue is produced, organized, and maintained by dermal fibroblasts. During aging, dermal collagen fibrils undergo...

... brain can be recognized by serum samples of BP patients with ND (BP+ND), indicating the possibility that BPAG1 could act as a shared autoantigen of the skin and brain. However, it is not known whether the serum of BP+ND patients could recognize BPAG1 in the human brain. Objectives: The aim of this study...

...M.C. Branchet; S. Boisnic; C. Frances; A.M. Robert The age-dependent decrease of skin thickness was studied with a morphometric procedure on upper inner arm skin biopsies. Epidermal thickness decreased somewhat faster in men (7.2 % of the original value/decade) than in women (5.7 %). The total...

... = 9). We performed glucocorticoid receptor-mediated skin vasoconstrictor responses to clobetasol and low-dose dexamethasone suppression tests. Patients with AD showed skin blanching at a significantly higher clobetasol concentration than did healthy elderly controls (p = 0.002...

...C. Robert; C. Lesty; A.M. Robert We quantitated the skin elastic fibers of the papillary and reticular dermis using specific staining procedure followed by automated computerized image analysis. Fifty skin biopsies of patients consulting for cardiovascular risk factors were studied. The following...

...Catherine Robert; Michel Blanc; C. Lesty; Shabtay Dikstein; Ladislas Robert Skin ageing was studied with a noninvasive method: indentometry. We measured two rheological parameters: resistance to pressure, indentation, under the pressure of 10 g/cm2, and elastic rebound, elasticity, after...

... and compared with those of a young group. The cutaneous histological ageing type was studied in the three groups. No histological difference was seen to exist between the two elderly populations (skin type II), the young group had normal type 0 skin. A significant difference was seen to exist between...

...H.N. Behera; B.K. Patnaik Alloxan diabetes in Swiss mice of both sexes accelerated the ageing of collagen in newly formed cotton pellet granuloma concomitant with its similar effect on dorsal skin. The degree of response of collagen to alloxanization was dependent on the duration of the treatment...

... the morphometric parameters of elastic fibers from the skin and the temporal artery in elderly subjects. Methods: we quantitated the skin elastic fibers of the reticular dermis and the elastic fibers of the temporal artey using a specific staining procedure followed by automated image analysis in 16 subjects...

...G.E. Piérard; F. Henry; D. Castelli; G. Ries Ageing affects the mechanical properties of skin. Studies using objective measurements on facial skin have been rare and yielded contradictory information. In the present study, the age-related changes occurring in the mechanical properties of facial...