...Ji Sup Hwang; Hyun Jung Kwon; Hyun Sik Gong Introduction: Animal studies suggest that advanced glycation end products (AGEs) and their interaction with receptor for AGEs (RAGE) are involved in sarcopenia, but their relationship in human skeletal muscles has yet to be elucidated. We aimed...

... subjected to 40% SCR for 30 days, followed by ad libitum feeding for 2 or 4 days. Liver, white adipose tissue (WAT), heart and skeletal muscle samples were analyzed by real-time PCR and Western blotting for SIRT7 mRNA and protein expression, respectively. Results: Aging had diverse effects on SIRT7 levels...

...Thomas A. White; Nathan K. LeBrasseur The progressive loss of skeletal muscle mass, strength and/or function with advancing age, termed sarcopenia , poses a major threat to independence and quality of life. Therefore, there is significant merit in better understanding the biology of sarcopenia...

... are limited. Interestingly though, endurance, strength and stretching exercise is significantly superior to all known pharmacological, nutritional and hormonal interventions for stabilizing, alleviating and reversing sarcopenia. Thus, increased knowledge about the plastic changes of skeletal muscle after...

..., University of Sao Paulo, Brazil Effects of Aging on Muscle Fibers and Collagen Content of the Diaphragm: A Comparison with the Rectus abdominis Muscle Key Words Diaphragm Aging Skeletal muscle Rectus abdominis Collagen Muscle fiber type Extracellular matrix A b stra ct Age-related changes of muscle fiber...

...L.L. Ji; E. Wu; D.P Thomas Aging is known to be associated with alterations of both oxidative capacity and antioxidant status in skeletal muscle. In the present investigation we compared the activity of enzymes involved in both metabolic functions and antioxidant defense capacity in young adult (5...

...Peter Möller; Anders Alvestrand; Jonas Bergström; Peter Fürst; Kjell Hellström Electrolytes and/or amino acids were determined in leg skeletal muscle biopsies from elderly (age range 57–75 years) and young (age range 20–35 years) apparently healthy women. When compared to the young group...

... Skeletal muscle Fibre length Sarcomere length Sarcomere number Fibre number Fibre diameter Experimental Section Gerontology 27: 121-126 (1981) Length, Diameter and Number of Ageing Skeletal Muscle Fibres A.C.B. Hooper Department of Anatomy. University College, Dublin, Ireland Key Words. Mouse...

...C.J. Lammi-Keefe; P.B. Swan; P.V.J. Hegarty The activities of total superoxide dismutase (SOD) and the manganese (Mn SOD) and copper-zinc (Cu-Zn SOD) forms were determined in the supernatant fraction of heart, liver and six skeletal muscles from rats during aging. Total SOD activity increased...

...M.A. Haseeb; B.K. Patnaik The collagenous/noncollagenous protein ratio in the skeletal muscle of the male garden lizard increased with advancing age, suggesting increased tensile strength of aged muscle. The solubility of collagen and the solube/insoluble collagen ratio showed a decline during...

...M.C. McNamara; A.T. Miller, jr.; A.L. Shen; J.J. Wood The rates of restitution of skeletal muscle, heart, and brain creatine phosphate and brain ATP, following experimental depletion, were compared in young (3–5 month), adult (12 month) and old (24 month) rats. In skeletal muscle, restitution...

...Josef Finsterer; Ellen Gelpi Objectives: Creutzfeldt-Jakob disease (CJD) is not only a disorder of the central nervous system but also affects the skeletal muscle. Subclinical skeletal muscle involvement, manifesting as hyper-creatine-kinase (CK)-emia, is rare. Case Report: The patient, a 60-year...