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Keywords: Serotonin
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Journal Articles
Journal: Gerontology
Gerontology (2024) 70 (4): 408–417.
Published Online: 16 January 2024
.... Finally, the expression of serotonin signaling and aging-related genes was investigated to explore the underlying mechanism, and the lifespan assays were performed in ser-7 RNAi strain, daf-2 , daf-16 , and aak-2 mutants. Results: Sertraline extended the lifespan in C. elegans with concomitant extension...
Journal Articles
Journal: Gerontology
Gerontology (2012) 59 (1): 23–31.
Published Online: 30 August 2012
... hypothalamic-pituitary-adrenal (HPA) axis activity, serotonergic transmission and hippocampal neurogenesis (perhaps via their effects on serotonin and HPA activity). These data tempt speculation that polyphenolic compounds could also combat age-related cognitive decline, which is often accompanied...
Journal Articles
Journal: Gerontology
Gerontology (1993) 39 (6): 305–313.
Published Online: 14 April 2009
... to in the content or advertisements. [14C]2-deoxyglucose Serotonin Meta-chlorophenyl-piperazine Aging Plasticity Experimental Section Gerontology 1993;39:305-313 Ulderico Freo Denise M. Larson Timothy T. Soncrant Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health...
Journal Articles
Journal: Gerontology
Gerontology (1988) 34 (1-2): 14–21.
Published Online: 07 April 2009
...V.D. Petkov; V.V. Petkov; S.L. Stancheva In experiments on 2-, 10- and 22-month-old rats it was found that the B max values of dopamine (DA 2 ), serotonin (5-HT 1 ) and enkephalin (Enk) receptors as well as th( 5-HT level in the three brain regions (cortex, striatum and hypothalamus) decreased...
Journal Articles
Journal: Gerontology
Gerontology (1987) 33 (3-4): 168–171.
Published Online: 07 April 2009
...W. Birkmayer; J.D. Birkmayer Disorders of neurotransmitter balance are observed in Parkinson’s disease, pharmacotoxic psychosis and depression. The dopamine-serotonin ratio is reduced to about 20% in Parkinson and pharmacotoxic patients in the caudate nucleus and in the substantia nigra...
Journal Articles
Journal: Gerontology
Gerontology (1987) 33 (3-4): 159–167.
Published Online: 07 April 2009
... on this problem. Brain neurotransmitters Dopamine Noradrenaline Serotonin Acetylcholine Aging Dementia Alzheimer’s disease Hippocampus Autoxidation © 1987 S. Karger AG, Basel 1987 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...
Journal Articles
Journal: Gerontology
Gerontology (1982) 28 (5): 303–313.
Published Online: 06 April 2009
... (norepinephrine and dopamine), but not serotonin (5-HT) changed with aging in the several brain regions, but only 5-HT was significantly changed (elevated) by ECS. Protein synthesis was significantly inhibited by ECS, notably in limbic structures. The increased susceptibility of aging mice to the amnesic effect...
Journal Articles
Journal: Gerontology
Gerontology (1980) 26 (5): 270–275.
Published Online: 06 April 2009
... Serotonin Gerontology 26: 270 -275 (1980) Effects of Centrally and Systemically Administered ¿-Tyrosine and ¿-Leucine on Ovarian Function in the Old Rat R.L. Cooper and M. Linnoila Center for the Study of Aging and Human Development, and Department of Psychiatry, Duke University Medical Center, Durham...
Journal Articles
Journal: Gerontology
Gerontology (1998) 44 (4): 211–216.
Published Online: 17 June 1998
...Adarsh M. Kumar; Sharlene Weiss; Jesus B. Fernandez; Dean Cruess; Carl Eisdorfer Serotonin has been implicated to play an important role in regulating emotions and behavior, and it is well accepted that the platelet serotonergic system mirrors the presynaptic central serotonergic system. Since...