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1-15 of 15
Keywords: Senescence
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Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2022) 68 (8): 920–934.
Published Online: 23 August 2022
...Ting Fan; Yi Du; Mingwan Zhang; Austin Rui Zhu; Jianjun Zhang Introduction: Senescent cells play a key role in the initiation and development of various age-related diseases. Human umbilical vein endothelial cells (HUVECs) senescence is closely associated with age-related cardiovascular diseases...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2021) 67 (5): 503–516.
Published Online: 02 August 2021
... disparity in biomarker levels and health status of ageing can be observed: the difference in CA and BA in the large cohorts under consideration is glaring. Here, we focus more closely on ageing and senescence metrics in order to make information available for risk analysis non the least with COVID-19...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2021) 67 (6): 708–717.
Published Online: 03 May 2021
..., the relationship between MITF and aging is attractive; however, the underlying mechanism remains elusive. Here, we review the documented cues that highlight the implication of MITF in the aging process and particularly discuss the possible mechanisms underlying the participation of MITF in cellular senescence...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2020) 66 (3): 223–230.
Published Online: 07 February 2020
... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Development Growth rate Longevity Aging Senescence IGF-1 Caloric restriction Telomere DNA damage National Institutes of Health (NIH) 10.13039/100000002...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Lutz Hamann, Juan S. Ruiz-Moreno, Malgorzata Szwed, Malgorzata Mossakowska, Linn Lundvall, Ralf R. Schumann, Bastian Opitz, Monika Puzianowska-Kuznicka
Journal:
Gerontology
Gerontology (2019) 65 (2): 145–154.
Published Online: 26 October 2018
... inflammation driving aging-related diseases. The aged immune system is characterized by the senescence-associated secretory phenotype, resulting in the release of proinflammatory cytokines contributing to inflamm-aging. Another possible mechanism resulting in inflamm-aging could be the increased release...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Jorge D. Erusalimsky, Johannes Grillari, Tilman Grune, Pidder Jansen-Duerr, Giuseppe Lippi, Alan J. Sinclair, Jesper Tegnér, Jose Viña, Anna Durrance-Bagale, Rebeca Miñambres, Marcelo Viegas, Leocadio Rodríguez-Mañas, on behalf of the FRAILOMIC Consortium
Journal:
Gerontology
Gerontology (2016) 62 (2): 182–190.
Published Online: 23 July 2015
... biomarkers associated with the risk of frailty will be identified. Genomic, proteomic and transcriptomic investigations will be carried out using array-based systems. As circulating microRNAs in plasma have been identified in the context of senescence, ageing and age-associated diseases, a miRNome-wide...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2014) 60 (6): 548–556.
Published Online: 09 July 2014
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Senescence Aging Trade-offs Regeneration Renewing Nonsenescence Maintenance While organisms across the tree...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2013) 60 (1): 49–55.
Published Online: 16 October 2013
...Mamoona Khan; Wilfried Rozhon; Brigitte Poppenberger Background: In plants, the final stage of organ development is termed senescence. This is a deterioration process that leads to the decay of tissues and organs, and that, in the case of annual, biennial and/or monocarpic plants, leads...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2012) 58 (5): 446–452.
Published Online: 06 April 2012
...Peter B. Gray; Justin R. Garcia In this mini-review, we consider an evolutionary biocultural perspective on human aging and sexuality. An evolutionary approach to senescence highlights the energetic trade-offs between fertility and mortality. By comparing humans to other primates, we situate human...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2011) 57 (6): 521–527.
Published Online: 15 December 2010
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Apoptosis Cell death Fluorescence Fruit Musa acuminata Senescence Experimental Section / Mini-Review Gerontology 2011;57:521 527 DOI...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (1994) 40 (1): 1–7.
Published Online: 14 April 2009
.... Staphylococcal alpha-toxin Senescence Erythrocytes Band 3 Experimental Section Gerontology 1994;40:1-7 Lana Kantor Hugh B. Fackrell Department of Biological Sciences, University of Windsor, Windsor, Ontario, Canada Differential Action of Staphylococcal Alpha-Toxin on Young and Old Erythrocytes Key Words...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (1983) 29 (5): 336–352.
Published Online: 08 April 2009
.... Lints, M. Bourgois, A. Delalieux, J. Stoll, C. V. Lints Laboratoire de Génétique. Université de Louvain. Louvain-la-Neuve, Belgium Key Words. Life span Drosophila Senescence Premature deaths Mean longevity Maximum longevity Abstract. A survey of all the papers relating to life span in Drosophila...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2008) 54 (3): 160–167.
Published Online: 25 March 2008
..., in particular ants and honey bees. While progress is being made in elucidating the interrelations between the vitellogenin, juvenile hormone, fecundity, and senescence, we feel that the explanation for the comparatively short lifespan of queens in multi-queen societies is as yet not satisfactory and needs...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2008) 54 (1): 24–31.
Published Online: 15 January 2008
... Aging Senescence Experimental Section Gerontology 2008;54:24 31 DOI: 10.1159/000113503 Published online: January 15, 2008 The Aging Cardiomyocyte: A Mini-Review D. Bernhard G. Laufer Cardiac Surgery Research Laboratory, Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (1998) 44 (1): 26–31.
Published Online: 10 December 1997
... of the alpha toxin which becomes disrupted by the age-related changes occurring in the receptor. 10 12 1997 Staphylococcal α-toxin Senescence Erythrocytes Band 3 Lana Kantor Hugh B. Fackrell Department of Biological Sciences, University of Windsor, Ont., Canada Experimental Section...