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Gerontology (2020) 66 (3): 212–222.
Published Online: 28 November 2019
... in this organism. In this review, we will explore how axolotls are used as a model system to study regenerative processes, the exciting new technological advancements now available for this model, and how we can apply the lessons we learn from studying regeneration in the axolotl to understand, and potentially...
Gerontology (2019) 65 (2): 174–185.
Published Online: 24 January 2019
...Magdalena M. Schimke; Swaraj Paul; Katharina Tillmann; Günter Lepperdinger; Robert G. Stigler Background: Due to aging, tissue regeneration gradually declines. Contemporary strategies to promote tissue-specific regeneration, in particular in elderly patients, often include synthetic material apt...
Gerontology (2018) 64 (3): 300–308.
Published Online: 10 January 2018
...Regina Brunauer; Ken Muneoka Aging is associated with a significant decline of tissue repair and regeneration, ultimately resulting in tissue dysfunction, multimorbidity, and death. Salamanders possess remarkable regenerative abilities and have been studied with the prospect of inducing...
Gerontology (2017) 63 (3): 270–280.
Published Online: 09 November 2016
... about the identity and function of these stem cell compartments has been largely drawn from a variety of transgenic and spontaneously mutated mouse models that are characterized by rapid rates of aging or have been used to examine regeneration from injury in the context of natural or accelerated aging...
Gerontology (2016) 63 (1): 91–100.
Published Online: 20 October 2016
... facet of sarcopenia is the diminished ability for aged muscle to regenerate, repair and remodel. Over the years, research has focused on elucidating underlying mechanisms of sarcopenia and the impaired ability of muscle to respond to stimuli with aging. Muscle-specific stem cells, termed satellite cells...
Gerontology (2014) 60 (6): 548–556.
Published Online: 09 July 2014
...Ralf Schaible; Meir Sussman; Boris H. Kramer Hydra present an interesting deviation from typical life histories: they have an extensive capacity to regenerate and self-renew and seem to defy the aging process. Hydra have the ability to decouple the aging process from their life history...
Gerontology (2012) 59 (1): 71–76.
Published Online: 22 September 2012
... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Extracellular matrix Regeneration...
Gerontology (2011) 57 (6): 565–571.
Published Online: 02 March 2011
...Catherine McCusker; David M. Gardiner Although regeneration of tissues occurs in all adult tetrapods, the ability to regenerate complex structures such as limbs is limited to urodeles (newts and salamanders). Given that many of the biological processes and the signaling pathways that control...
Gerontology (2010) 57 (1): 85–94.
Published Online: 06 May 2010
... can be achieved by programming progenitor stem cells to adopt dental lineages, using instructive, bioengineered scaffold materials. Periodontal ligament regeneration in particular has demonstrated significant progress recently, despite the somewhat unpredictable clinical outcomes, with regard to its...
Gerontology (2010) 56 (2): 231–240.
Published Online: 18 November 2009
...Tamara L. Tal; Jill A. Franzosa; Robert L. Tanguay This short review provides a current synopsis of caudal fin regeneration in zebrafish with an emphasis on the molecular signaling networks that dictate epimorphic regeneration. At the outset, the fundamentals of caudal fin architecture...
Gerontology (1994) 40 (2-4): 161–173.
Published Online: 14 April 2009
... Neurogenesis Myogenesis Regeneration A m p h ib ia Gerontology 1994;40:161-173 T.C. Kara Post Graduate Department of Life Science. S.K.C.G. College. Paralakhemundi. India Ageing in Amphibians Key Words Amphibia Age changes Collagen Age pigments Neurogenesis Myogenesis Regeneration Abstract Limited...
Gerontology (1976) 22 (4): 280–300.
Published Online: 03 April 2009
... are explained in terms of physiological changes in senescent motor units. The reactions of senescent motor units differ from one unit to another as shown, e.g. in denervation, reinnervation and regeneration (transplantation) studies. The trend to a shift from a heterogeneous to a more uniform muscle fibre...