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Keywords: Rat
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Journal Articles
Journal: Gerontology
Gerontology (2022) 68 (7): 790–798.
Published Online: 27 January 2022
... (4-month) and old (24-month) male Wistar rats were either fed ad libitum (control groups) or received 60% of food intake on a daily basis for 30 days (SCR groups). In blood sera, biochemical parameters and fibroblast growth factor 21 (FGF21) concentration were measured (ELISA). Liver samples were...
Journal Articles
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Journal Articles
Journal: Gerontology
Gerontology (1983) 29 (1): 9–18.
Published Online: 08 April 2009
...I.Yu. Khilobock; T.G. Mozzhukhina; V.N Chabanny; S.N. Kadura Thermal denaturation and electrophoretic mobility of liver and small intestinal mucosa fractionated chromatin and the DNA of chromatin fractions have been studied in young and old rats. During aging, the thermostability of chromatin...
Journal Articles
Journal: Gerontology
Gerontology (1983) 29 (6): 362–369.
Published Online: 08 April 2009
...Antonello Novelli; Daniela Cocchi; Gabriella Calderini; Gino Toffano; Eugenio E. Müller Baseline prolactin (PRL) levels and the PRL-lowering effect of nomifensine (Nom), an indirect dopamine (DA) agonist, were evaluated in young adult (3–5 months) and old (21 and 27 months) male rats. In addition...
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Journal Articles
Journal: Gerontology
Gerontology (1983) 29 (4): 248–261.
Published Online: 08 April 2009
...Avis L. Sylvia; Sami I. Harik; Joseph C. LaManna; Tim Wilkerson; Myron Rosenthal Cerebral oxidative metabolism was studied in vivo by monitoring redox shifts of cytochrome c oxidase in response to direct electrical stimulation of the cerebral cortex in Fischer-344 rats at 3 and 28 months of age...
Journal Articles
Journal: Gerontology
Gerontology (1987) 33 (2): 87–98.
Published Online: 07 April 2009
...R. Ravid; E. Fliers; D.F. Swaab; C. Zurcher Although earlier reports in the literature suggested degenerative changes in the senescent hypothalamo-neurohypophyseal system (HNS), recent investigation showed hy-peractivity of this system in the old Wistar (WAG/Rij) rat. In the brain, changes were...
Journal Articles
Journal: Gerontology
Gerontology (1987) 33 (2): 99–108.
Published Online: 07 April 2009
... protein deprivation on the febrile response to interleukin–1 (IL–1) and endotoxin in young, middle-aged, and elderly Fischer rats. In each age group, rats received either a standard (23% casein) or low protein (8% casein) diet for 5 weeks (young rats) or 8 weeks (middle-aged and elderly rats). Each rat...
Journal Articles
Journal: Gerontology
Gerontology (1988) 34 (5-6): 231–235.
Published Online: 07 April 2009
...Alberto Ricci; Elena Bronzetti; Francesco Amenta The age-related changes in the number and density of optic nerve fibres were studied in 3-month-old (young), 12-month-old (adult), 20-month-old (senescent) and 30-month-old (aged) male Wistar rats. Two-micrometer-thick resin-embedded transverse...
Journal Articles
Journal: Gerontology
Gerontology (1980) 26 (3): 121–128.
Published Online: 06 April 2009
...Rick Ekstrom; Daniel S.H. Liu; Arlan Richardson The cell-free protein synthetic activity of the postmitochondrial supernatant isolated from whole brain of 6- to 32-month-old male Fischer F344 rats was compared. Protein synthesis decreased 56% from 6 to 32 months of age. The decrease in cell-free...
Journal Articles
Journal: Gerontology
Gerontology (1980) 26 (1): 9–15.
Published Online: 06 April 2009
...A. Weber; C. Guguen-Guillouzo; M.F. Szajnert; G. Beck; F. Schapira We have studied tyrosine aminotransferase in the liver of adult and old rats. Thermostability and trypsin action were not modified, and no charge differences have been found by isoelectric focusing between ‘adult’ and ‘old’ enzymes...
Journal Articles
Journal: Gerontology
Gerontology (1980) 26 (2): 61–67.
Published Online: 06 April 2009
...S. Mohan; E. Radha Age-related studies of collagen in slow, fast and cardiac muscle of the rat indicate that different fractions of collagen as well as total collagen content vary with age and type of muscle. The total collagen level increases by 30% in slow, 40% in fast and 50% in cardiac muscle...
Journal Articles
Journal: Gerontology
Gerontology (1980) 26 (6): 321–326.
Published Online: 06 April 2009
...E.L. Levitsky Replicating spleen and kidney DNA of 6-month (adult) and 24-month (old) rats labeled with 3 H-thymidine was separated to single-stranded and double-stranded fractions by hydroxyapatite chromatography. The relative quantity of single-stranded DNA was decreased during labeling...
Journal Articles
Journal Articles
Journal: Gerontology
Gerontology (1984) 30 (2): 87–93.
Published Online: 06 April 2009
...D. Bhaskaran; E. Radha The inhibitory effect of procaine hydrochloride and Gerovital-H3 on monoamine oxidase (MAO) activity in the rat brain was studied at six time points during the 24-hour cycle. It was found that the percent inhibition is time dependent. Both drugs showed maximum inhibition when...
Journal Articles
Journal: Gerontology
Gerontology (1984) 30 (2): 120–124.
Published Online: 06 April 2009
...Adria Rothman Sherman; Barbara A. Kochanowski; Ira Wolinsky Lysozyme, peroxidase, serum proteins, and immunoglobulins were measured in young (1 month), mature (13 months), and aged rats (25 months). Circulating levels of immunoglobulins G and A increased with maturity as did the globulin fraction...
Journal Articles
Journal: Gerontology
Gerontology (1982) 28 (4): 233–241.
Published Online: 06 April 2009
...Charles L. Goodrick; Donald K. Ingram; Mark A. Reynolds; John R. Freeman; Nancy L. Cider From weaning to death, 28 male Wistar rats were maintained on an ad libitum (AL) diet, and 24 counterparts were provided the diet every-other-day (EOD). The mean life span of the EOD group represented an 83...
Journal Articles
Journal: Gerontology
Gerontology (1981) 27 (1-2): 37–41.
Published Online: 06 April 2009
...Arthur V. Everitt; Barbara D. Porter; Matthew Steele The effect of dietary fat, carbohydrate and protein on tail tendon collagen ageing was studied in male Wistar rats. When rats were fed low-calorie diets there was no evidence that the content of carbohydrate, fat or protein affected the ageing...
Journal Articles
Journal: Gerontology
Gerontology (1981) 27 (1-2): 7–12.
Published Online: 06 April 2009
...Vesna Cvejić; B.B. Mršulja The turnover rate of catecholamine in the cerebral cortex and caudate of adult Wistar rats was estimated after inhibition of synthesis by means of α -methyl- p -tyrosine in animals treated with dihydroergotoxine (1 mg/kg body weight daily) for 1, 3 and 10 days. Following...