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Keywords: Progeria
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Journal Articles
Journal: Gerontology
Gerontology (2016) 63 (1): 84–90.
Published Online: 20 October 2016
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Reprogramming Stem cells Progeria Aging With the HSC environment being pivotal in regulating HSC function, it comes as no surprise that, so far, no significant life...
Journal Articles
Journal: Gerontology
Gerontology (1986) 32 (4): 202–206.
Published Online: 15 April 2009
... Fibroblasts Lewis C. Mokrasch Department of Biochemistry, LSU Medical Center, New Orleans, La., USA Key Words. Fibroblasts Progeria ATPase y-Glutamyl transpeptidase 5'-Nucleotide phosphatase Plasmalemma WI38 cells Abstract. Cell membranes from progeroid fibroblasts had an elevated Na+, K+ ATPase...
Journal Articles
Journal: Gerontology
Gerontology (1990) 36 (2): 84–98.
Published Online: 08 April 2009
... into ageing, the problem must first be simplified by restricting studies to an aspect of the ageing processes. It is suggested that progeria, which presents a less complicated etiology and phenotype than other accelerated ageing diseases, allows research to focus on a regulation site involved in development...
Journal Articles
Journal: Gerontology
Gerontology (1983) 29 (2): 73–82.
Published Online: 08 April 2009
.... The longevity of fibroblasts from one progeria patient was also shown to be much shorter than controls. Metaphases from 3 Werner’s patients demonstrated a much higher frequency of chromosome abnormalities than in normal fibroblasts and also provided evidence of subclones containing a characteristic ‘marker...
Journal Articles
Journal: Gerontology
Gerontology (1983) 29 (2): 89–96.
Published Online: 08 April 2009
...R. Holliday; K.V.A. Thompson The level of heat-labile glucose-6-phosphate dehydrogenase (G6PD) has been measured in skin fibroblast cultures from premature ageing or DNA repair deficient genetic syndromes. The short in vitro longevity of Werner’s syndrome, progeria, Cockayne’s syndrome, ataxia...
Journal Articles
Journal: Gerontology
Gerontology (1992) 38 (3): 139–152.
Published Online: 08 April 2009
.... However, it is not known whether the increase in HA excretion seen in progeria patients is due to a primary genetic defect or is a secondary effect due to some deeper problem. The phenomenon of ‘normal’ aging is suggested to have a more complex etiology and phenotype than progeria and the role of HA...
Journal Articles
Journal: Gerontology
Gerontology (1981) 27 (4): 181–186.
Published Online: 06 April 2009
...Sudhir Gupta Peripheral blood from 4 patients with progeria and their family members and 2 patients with Werner’s syndrome were analyzed for the proportion of total T cells and T cells with receptors for I g M (Tμ) or I g G (Tγ). In 3 patients proportions of Tμ cells were within the range for age...
Journal Articles
Journal: Gerontology
Gerontology (1978) 24 (5): 373–380.
Published Online: 03 April 2009
...John Caldwell; Robert L. Smith; Sian A. Davies A case of premature ageing (progeria) in a 3-year-old Indian child is described. The conjugations of paracetamol with glucuronic acid and sulphate, of benzoic acid with glycine and of phenylacetic acid with glutamine have been investigated...