...R. Brudieux; J. Rakotondrazafy Age-related changes in plasma aldosterone and corticosterone concentrations as well as in plasma renin activity in response to 10 days of sodium deprivation were studied in old as compared to adult male Long-Evans rats. Chronic sodium deprivation greatly increased...

... ± 9 to 165 ± 21/91 ± 13 mm Hg), but only 35% of patients attained a normal pressure. Heart rate did not change with treatment. Enalapril caused an increase in plasma renin activity (1.22 ± 0.08 to 3.66 ± 2.50 ng/ml/h), whereas aldosterone levels remained unchanged. There was a mild, significant...

... hypertensive patients tend to have low plasma renin activity. We have investigated this situation in a large postmarketing surveillance study with enalapril. Following a 2-week no-treatment period, a total of 11,710 patients with essential hypertension received 10–20 mg of enalapril once daily for 6 weeks. BP...

...G. Annat; M. Vincent; A. Tourniaire; J. Sassard Plasma renin activity (PRA), aldosterone (PA) and dopamine-β-hydroxylase activity (DBH) were measured in 49 subjects over 70 years of age, selected for normal or high blood pressure level. By comparison with younger controls, elderly subjects...