... expression Oxidative stress © 2023 S. Karger AG, Basel Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying...

... of DBI, oxidative stress, inflammatory, and neurodegenerative biomarkers were compared between 3 groups. Results: Plasma levels of DBI, oligomeric Aβ, total tau, glial fibrillary acidic protein, α-synuclein, interleukin (IL) 1β, IL6, tumor necrosis factor α, oxidative stress index, high-sensitive C...

... does not induce renal damage, underlying disease such as diabetes mellitus can aggravate kidney injury during aging. Although oxidative stress is considered an important mediator in age-related renal fibrosis, it is unclear how oxidative stress increases during normal and diabetic aging. Methods...

... in the intestinal barrier, which was accompanied by the reduction of TNF-α level. The expression of receptors of intestinal GLP-2 and vitamin D in the ileum was elevated. Furthermore, the oxidative stress in the intestines was improved by increasing the GPX-4 and SOD-2 signaling. Conclusion: Our findings suggest...

... significantly induced cardiac aging, cell apoptosis, and oxidative stress in Nrf2 +/+ mice, all of which were further exacerbated in Nrf2 –/– mice. CDDO-Im treatment can effectively weaken oxidative stress and enhance the activities of antioxidant enzymes, but CDDO-Im lost its antioxidative effect in the Nrf2...

..., organs, and organisms over time. Elevated oxidative stress is also found in metabolic diseases such as obesity, metabolic syndrome and associated disorders. Moreover, dysregulation of the energy homeostasis is also associated with aging, and many age-related genes also control energy metabolism...

... is differentially regulated by a wide variety of stimuli due to the combined presence of many distinct regulatory elements in its promoter that make it an extremely sensitive cellular biosensor of environmental and/or oxidative stress. Downstream to CLU gene induction, the CLU protein seems to actively intervene...

... on the interplay of oxidative stress and complement dysregulation and the resulting chronic proinflammatory state thought to be central in AMD pathogenesis. Conclusions: Oxidative stress and complement dysregulation play a substantive role in the development of AMD. 31 10 2012 29 11 2012 8 2 2013...

... reflect the in vivo characteristics of single satellite cells from adult skeletal muscle. Methods: We established a myoblast mixed culture and three myoblast clonal cultures out of the same muscle biopsy and cultured these cells for 100 days. Replicative capacity and oxidative stress resistance were...

...Simona Jurkovic Mlakar; Janez Prezelj; Josko Osredkar; Janja Marc Background: Much research suggests that oxidative stress is associated with osteoporosis development. Glutathione S-transferases mu3 (GSTM3) are an important group of detoxifying enzymes that eliminate oxidative stress-related...

...Jing-Zhi Guan; Wei-Ping Guan; Toyoki Maeda; Naoki Makino Background: Oxidative stress (OS) may be involved in the neurodegenerative process in Alzheimer’s disease (AD). Telomeres, the repeated sequences that cap chromosome ends, undergo shortening with each cell division, are sensitive to OS...

... of age [74-77], Thus, after life-long free radical insult, the brain shows a number of morphological and functional deficits. How­ ever, analyses of constituent levels of some indices of oxidative stress have not given con­ sistent data. Lipid peroxidation and Cu-Zn superoxide dismutase activity...

...P.M. Schwartsburd A comparision of the response of different cell types (thymus, spleen, liver, tumor) to the development of oxidative stress was investigated on an experimental model of tumor growth in vivo. Only spleen cells exhibited the yellow-red fluorescent pigment with high resistance...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Age Pigments Aging Carbonyls Ceroid-lipofuscin Glycation Oxidative Stress STUDIES ON AGE PIGMENTS EVOLVING INTO A NEW THEORY OF BIOLOGICAL AGING Dazhong Yin Department...

... to in the content or advertisements. Oxidative stress Vitamin E Selenium Copper-zinc superoxide dismutase (CuZnSOD) Lipofuscin Ceroid Pigs DIET-INDUCED RESIDUAL FORMATION IN PIGS B.G. de Gritz and T. Rahko Pathological Anatomy, College of Veterinary Medicine, Box 6, 00581 Helsinki, FINLAND Key Words...

... in diabetes. Free radicals Diabetes mellitus Oxidative stress Vitamin C (ascorbic acid) Antioxidants 31 12 1991 28 03 1992 8 4 2009 Clinical Section Gerontology 1992:38:268-274 A.J. Sinclair A.J. Girling L. Gray J. Lnnec A.H. Barnett Academic Departments of Geriatric Medicine...

... of oxidant damage with aging. Furthermore, the ability to mount an effective response to oxidative stress (induction of oxidant stress genes and proteins) may decline with age, thus predisposing older cells and organisms to oxidant damage. 8 4 2009 © 1991 S. Karger AG, Basel 1991 Copyright...

... oxidative modifications of proteins as well as on mechanism for removal or repair of the oxidized proteins. The topics covered include protein oxidation as a marker of oxidative stress, experimental evidence indicating the role of ROS in protein oxidation, protein carbonyl content, enzymatic degradation...

...Gulgun S. Guven; Mehmet Guven; Ilhan Onaran; Aydın Tunckale; Seniha Hacihanefioglu; Turgut Ulutin Background: A large number of studies have demonstrated that various kinds of DNA damage accumulate during aging and that oxidative stress possibly contributes to this process. Glutathione S...

...Mitsuyoshi Matsuo; Hidefumi Ikeda; Takehiko Sugihara; Satomi Horiike; Yuri Okano; Hitoshi Masaki Background: It has been suggested that oxidative stress is involved in the aging process and that the resistance of animals to oxidative stress may decrease with advancing aging. However, there are only...