... be influenced by SUMOylation. Similarly, SUMOylation is essential for proper neuronal function. In this review we summarize the latest results regarding the connection between SUMOylation and neurodegenerative diseases. We highlight the significance of specific SUMO target proteins and the importance of SUMO...

...G.J.C.G.M. Bosman; K. Renkawek; F.P.A. Van Workum; I.G.P. Bartholomeus; W.J. De Grip Anion exchange (AE) proteins are present in human neurons in the brain. Immunohistochemical data indicate that their apparent expression level increases with age, and especially with degeneration in Alzheimer’s...

... precursor protein (APP). Cell fractionation and immunological studies on the APP molecule indicate that APP is localized either in the neuron and astrocyte and that the molecule is recovered from lysosomal fraction. 14 4 2009 © 1993 S. Karger AG, Basel 1993 Copyright / Drug Dosage...

.... Compatible with the possible role of APP in cell-matrix interaction, an increase in oligodendroglial APP was observed following their attachment onto poly- L -lysine substratum. Neuron Astrocyte Oligodendrocyte Microglia Tissue culture Immunoblotting β-Amyloid precursor protein 8 4 2009...