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Keywords: Mitochondrial function
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Journal Articles

Testosterone Deprivation Aggravates Left-Ventricular Dysfunction in Male Obese Insulin-Resistant Rats via Impairing Cardiac Mitochondrial Function and Dynamics Proteins

Subject Area:
Geriatrics and Gerontology
Nattayaporn Apaiajai, Titikorn Chunchai, Thidarat Jaiwongkam, Sasiwan Kerdphoo, Siriporn C. Chattipakorn, Nipon Chattipakorn
Journal: Gerontology
Gerontology (2018) 64 (4): 333–343.
https://doi.org/10.1159/000487188
Published Online: 26 June 2018
...) and orchiectomy (NDO, HFO). Metabolic parameters, blood pressure, heart rate variability (HRV), and LV function were determined at baseline and before and after orchiectomy. Mitochondrial function and dynamics proteins, insulin signaling, and apoptosis were determined 12 weeks postoperatively. Results: HFS rats...
View article titled, Testosterone Deprivation Aggravates Left-Ventricular Dysfunction in Male Obese Insulin-Resistant Rats via Impairing Cardiac <span class="search-highlight">Mitochondrial</span> <span class="search-highlight">Function</span> and Dynamics Proteins
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Journal Articles

Mitochondrial Function and Insulin Resistance during Aging – A Mini-Review

Subject Area:
Topic Article Package: Diabetes , Geriatrics and Gerontology
Esther Phielix, Julia Szendroedi, Michael Roden
Journal: Gerontology
Gerontology (2011) 57 (5): 387–396.
https://doi.org/10.1159/000317691
Published Online: 28 August 2010
.... Conclusions: In the elderly, low mitochondrial oxidative capacity likely results from age-related effects acquired during life span. Insulin resistance occurs independently of age mostly due to unhealthy lifestyle on top of genetic predisposition. Thus, insulin sensitivity and mitochondrial function may...
View article titled, <span class="search-highlight">Mitochondrial</span> <span class="search-highlight">Function</span> and Insulin Resistance during Aging – A Mini-Review
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