...Sonia Navarro; Barbara Driscoll Natural lung aging is marked by molecular changes that occur during development, maturation, and late-life decline. At the cellular and whole organ level, degenerative changes that are a hallmark of natural aging (shorter telomeres, increased expression of cellular...

... and utilization. Integrated changes of the heart-lung muscle axis are termed here ‘coordinated deadaptation', e.g. due to aging and disease, in contrast to the beneficial effects of ‘coordinated adaptation', e.g. resulting from exercise training. Physical inactivity in aging persons initiates a circulus vitiosus...

...Harold H. Traurig The activities of four lysosomal acid hydrolases (LAH) in the lungs of two strains of mice changed significantly throughout the life cycle. In the C57B1/6J animals, acid phosphatase (AP) and β- glucuronidase (β-G) were maximally active during early neonatal life then gradually...

... remains to be clarified. Objective: In this experimental study, we investigated the age-related changes of malondialdehyde (MDA), a lipid peroxidation product, and glutathione (GSH) and the effects of exogenous melatonin. Methods: Plasma, liver, and lung MDA and GSH levels of 9- and 28-month-old rats were...