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Keywords: Liver
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Journal Articles
Journal: Gerontology
Gerontology (2022) 68 (7): 790–798.
Published Online: 27 January 2022
...Agata Wrońska; Adrian Zubrzycki; Zbigniew Kmieć Introduction: Short-term calorie restriction (SCR) may have a positive impact on health. We hypothesized that sestrins, a family of stress-inducible proteins (Sesn1, Sesn2, Sesn3) are involved in the response to SCR in the liver. Methods: Young-adult...
Journal Articles
Journal: Gerontology
Gerontology (2016) 62 (3): 304–310.
Published Online: 01 March 2016
... subjected to 40% SCR for 30 days, followed by ad libitum feeding for 2 or 4 days. Liver, white adipose tissue (WAT), heart and skeletal muscle samples were analyzed by real-time PCR and Western blotting for SIRT7 mRNA and protein expression, respectively. Results: Aging had diverse effects on SIRT7 levels...
Journal Articles
Journal: Gerontology
Gerontology (1993) 39 (Suppl. 1): 3–10.
Published Online: 14 April 2009
...Y. Miyamura; H. Ohtsu; O. Niwa; A. Kurishita; H. Watanabe; T. Sado; T. Ono Study of DNA methylation of the c- myc gene in liver tumors of BCF 1 mice treated with various agents revealed frequent alteration from that in normal liver. The alteration, however, was complex and showed either an increase...
Journal Articles
Journal: Gerontology
Gerontology (1990) 36 (5-6): 262–267.
Published Online: 08 April 2009
... responsive than the old counterparts. Lizard Liver Glucose uptake Starvation Cold stress © 1990 S. Karger AG, Basel 1990 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form...
Journal Articles
Journal Articles
Journal: Gerontology
Gerontology (1990) 36 (2): 61–75.
Published Online: 08 April 2009
...G.H. Park; D.E. Buetow Nuclei isolated from senescent (22–26 months) female Wistar rat liver show a decreased RNA synthesis compared to nuclei from adult (12 months) liver. Kinetic analyses demonstrate a decreased rate (25–42%) and maximal incorporation (41–54%) of labeled uridine triphosphate...
Journal Articles
Journal: Gerontology
Gerontology (1983) 29 (1): 9–18.
Published Online: 08 April 2009
...I.Yu. Khilobock; T.G. Mozzhukhina; V.N Chabanny; S.N. Kadura Thermal denaturation and electrophoretic mobility of liver and small intestinal mucosa fractionated chromatin and the DNA of chromatin fractions have been studied in young and old rats. During aging, the thermostability of chromatin...
Journal Articles
Journal: Gerontology
Gerontology (1988) 34 (5-6): 257–263.
Published Online: 07 April 2009
...Albert P. Shih; Vlasta K. Zbuzek; Frank C. Sauchelli; Wen-hsien Wu The effect of aging on vasopressin (VP) clearance was studied in male Fischer 344 rats 2 (young), 12 (adult) and 30 (old) months of age using in situ liver perfusion technique. The liver was perfused with Krebs-Henseleit bicarbonate...
Journal Articles
Journal: Gerontology
Gerontology (1982) 28 (3): 149–155.
Published Online: 06 April 2009
...T. Vömel; D. Platt The rate of phagocytosis of 59 Fe-labeled erythrocytes of various ages was measured in the rabbit. Liver, spleen and the remaining parts of the reticulohistiocytic system (RHS) were compared with each other. The phagocytic activity in the liver increased from 66% in 4-day-old...
Journal Articles
Journal: Gerontology
Gerontology (1985) 31 (2): 95–100.
Published Online: 06 April 2009
...H. Cao Danh; M. Strolin Benedetti; P. Dostert Glutamine synthetase (GS) activity was measured in whole brain, different brain areas, liver and heart of 23- to 26-month-old rats, and then compared to matched animals of 3 months. A significant increase of GS activity was found in whole brain (25...
Journal Articles
Journal: Gerontology
Gerontology (1984) 30 (3): 159–166.
Published Online: 06 April 2009
...H. Cao Danh; M. Strolin Benedetti; P. Dostert Aldehyde reductase (AR) activity was measured in the brain, liver and heart of 23- to 26-month-old and 3-month-old male Wistar rats, using 5 substrates ( p -nitrobenzalde-hyde, D -glucuronate, D -xylose, DL -glyceraldehyde and pyridine 3-aldehyde...
Journal Articles
Journal: Gerontology
Gerontology (1980) 26 (1): 9–15.
Published Online: 06 April 2009
...A. Weber; C. Guguen-Guillouzo; M.F. Szajnert; G. Beck; F. Schapira We have studied tyrosine aminotransferase in the liver of adult and old rats. Thermostability and trypsin action were not modified, and no charge differences have been found by isoelectric focusing between ‘adult’ and ‘old’ enzymes...
Journal Articles
Journal Articles
Journal: Gerontology
Gerontology (1979) 25 (6): 314–321.
Published Online: 06 April 2009
... polymorphism and a variation in matrical density. Lysosomes and autophagic vacuoles as well as lipid droplets of various sizes were frequent in all groups. These results show that microsomal enzyme inducers influence the subcellular structure of hepatocytes in old rats. Liver Rats Enzyme inducers...
Journal Articles
Journal: Gerontology
Gerontology (1979) 25 (4): 219–227.
Published Online: 06 April 2009
...Zh.A. Medvedev; M.N. Medvedeva; L. Robson The non-histone chromatin (NHC) proteins which are loosely bound to DNA were extracted from young and old mouse and rat liver chromatin by 0.35 M NaCl and fractionated into three groups: water-soluble, 0.14 M NaCl soluble and 0.35 M NaCl soluble. NHC...
Journal Articles
Journal: Gerontology
Gerontology (1977) 23 (5): 342–349.
Published Online: 03 April 2009
...Lynn S. Grinna Arrhenius plots of glucose-6-ρhosphatase (EC 3.1.3.9) activity in liver microsomes from 6-month-old rats (young) showed discontinuities at 39, 30, 20 and 12 °C and change in activation energy at 20 °C. The enzyme activity in kidney microsomes of young rats showed essentially the same...
Journal Articles
Journal: Gerontology
Gerontology (1977) 23 (5): 334–341.
Published Online: 03 April 2009
... was extracted from chromatin separately by perchloric acid and purified by Biogel P-60 column chromatography from chromatin of rat liver and spleen, the polyacrylamide gel electrophoresis did show obvious age changes in the distribution of F1, F1°, and F1°° subfractions. In liver chromatin the increase of rat...
Journal Articles
Journal: Gerontology
Gerontology (1978) 24 (5): 348–357.
Published Online: 03 April 2009
...Patricia D. Wilson In the livers from young (3–6 month) and old (30 month) C57/BL mice and BN/Bi rats light microscope histochemistry has shown that enzyme activity is not always distributed evenly throughout the lobule. The mitochondrial enzyme succinic dehydro-genase, the plasma membrane enzyme 5...
Journal Articles
Journal: Gerontology
Gerontology (1978) 24 (4): 286–292.
Published Online: 03 April 2009
... a different pattern of HI histone fraction and subfraction. However, the age-associated changes of mouse HI histones from liver and spleen chromatin show the same type of alteration of fraction ratios which had been demonstrated in our earlier research with rat tissues. In both species there is a relative...
Journal Articles
Journal: Gerontology
Gerontology (1978) 24 (1): 32–36.
Published Online: 03 April 2009
...R.L. Eichholz; D.E. Buetow The total free amino acid content per gram of liver wet weight does not differ significantly between adult and senescent female rats, being 28.8 ± 3.3 µmol in adult (13–17 months) and 26.2 ± 2.2 µmol in senescent (23–29 months) animals. This is the first study in which...