... Risk factors Frailty Inflammation Metabolic syndrome Lipids Insulin resistance With increased life expectancy, the number of individuals living with multimorbidity rises rapidly [ 1 ]. It is estimated that 55%–98% of older adults are affected by more than one chronic health condition [ 2...

...Carlo M. Barbagallo; Maurizio R. Averna; Giovanni Fradà; Salvatore Chessari; Giuseppe Mangiacavalllo; Alberto Notarbartolo The relation between plasma lipids and coronary heart disease (CHD) in the elderly is still debated, as well as the proposed role of lipoproteins as markers of longevity...

... and subsequent proteolysis. These are implicated as causative factors in red cell aging, immunoglobulin binding and recognition of senescent erythrocytes. 8 4 2009 Erythrocyte membrane Proteins Lipids Deformability Surface charge Fluidity Reactive oxygen species Proteolysis Immunoglobulin G...

...Meir Shinitzky The lipid composition of cell plasma membranes reflects a steady-state between accumulation of serum lipids, predominantly cholesterol, and intracellular lipid synthesis and degradation. In the aging tissue this subtle balance is impaired with a net accumulation of cholesterol...

... of BAPN did not produce plasma lipid abnormalities such as those due to hyperlipidic diet. 9 weeks of BAPN followed by 10 months of a hyperlipidic diet increased the aortic cholesterol level and induced atheroma. The diet alone only produced an endothelial lipid overload and increased the aortic...