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1-20 of 36
Keywords: Inflammation
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Journal Articles
Healthy Aging at Moderate Altitudes: Hypoxia and Hormesis
Available to PurchaseSubject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2024) 70 (11): 1152–1160.
Published Online: 30 September 2024
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Oxygen Age-related diseases Mortality Hypoxia-inducible factor Inflammation During aging, the efficiency of cells and organs...
Journal Articles
Reduction in Renal Interstitial Fibrosis in Aged Male Mice by Intestinal Microbiota Rejuvenation
Available to PurchaseSubject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2024) 70 (11): 1161–1170.
Published Online: 13 August 2024
... array. Senescence-associated β-galactosidase and Masson staining were performed to observe the degrees of renal senescence and tubule interstitial fibrosis. Immunohistochemistry was utilized to detect changes in the expression of the ageing markers p53 and p21 and the inflammation-related protein...
Journal Articles
Application of Multiple Omics to Understand Postoperative Delirium Pathophysiology in Humans
Open Access
Journal:
Gerontology
Gerontology (2023) 69 (12): 1369–1384.
Published Online: 18 September 2023
... innovative proteomics platforms (described in the section on “Unbiased Mass Spectrometric Proteomics”) have revolutionized and accelerated progress in the field. Until quite recently, most studies of delirium pathophysiology have focused on pre-selected candidate proteins associated with inflammation...
Journal Articles
Journal:
Gerontology
Gerontology (2023) 69 (9): 1104–1112.
Published Online: 22 August 2023
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Diazepam binding inhibitor Alzheimer’s disease Ageing Biomarker Inflammation Oxidative stress Blood taken from volunteers into heparinized tubes...
Journal Articles
Role of NADPH Oxidases in Renal Aging
Open AccessSubject Area:
Topic Article Package: ADC (Antibody-Drug Conjugates)
, Karger e-Journal Backfile Collection 2023
, Geriatrics and Gerontology
Sung Gi Yoon, Jung Yeon Ghee, Ji Ae Yoo, Boo Yeun Park, Jin Joo Cha, Young Sun Kang, Sang Youb Han, Hye Sook Min, Ji Eun Lee, Jee Young Han, Dae Ryong Cha
Journal:
Gerontology
Gerontology (2023) 69 (7): 852–865.
Published Online: 04 July 2023
... as biologically aging mice in this study. In this study, we investigated chronological changes in the kidney in biologically aging mice and diabetic aging mice with a focus on inflammation, fibrosis, and oxidative stress markers associated with renal functional as well as structural changes in the kidneys...
Journal Articles
Multimorbidity and Functional Disability among Older Adults: The Role of Inflammation and Glycemic Status – An Observational Longitudinal Study
Available to PurchaseSubject Area:
Topic Article Package: ADC (Antibody-Drug Conjugates)
, Karger e-Journal Backfile Collection 2023
, Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2023) 69 (7): 826–838.
Published Online: 04 July 2023
... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Multimorbidity combinations Disability Inflammation Glycemic status Biomarkers...
Journal Articles
Association of Torquetenovirus Viremia with Physical Frailty and Cognitive Impairment in Three Independent European Cohorts
Available to PurchaseSubject Area:
Topic Article Package: ADC (Antibody-Drug Conjugates)
, Karger e-Journal Backfile Collection 2023
, Geriatrics and Gerontology
Robertina Giacconi, Blanca Laffon, Solange Costa, Armanda Teixeira-Gomes, Fabrizio Maggi, Lisa Macera, Pietro Giorgio Spezia, Francesco Piacenza, Alexander Bürkle, María Moreno-Villanueva, Stefano Bonassi, Vanessa Valdiglesias, Joao Paulo Teixeira, Martijn E.T. Dollé, M. Liset Rietman, Eugène Jansen, Tilman Grune, Efstathios S. Gonos, Claudio Franceschi, Miriam Capri, Birgit Weinberger, Ewa Sikora, Wolfgang Stuetz, Olivier Toussaint, Florence Debacq-Chainiaux, Antti Hervonen, Mikko Hurme, P. Eline Slagboom, Christiane Schön, Jürgen Bernhardt, Nicolle Breusing, Eduardo Pásaro, Ana Maseda, Laura Lorenzo-López, José Carlos Millán-Calenti, Mauro Provinciali, Marco Malavolta
Journal:
Gerontology
Gerontology (2023) 69 (6): 684–693.
Published Online: 06 June 2023
... to in the content or advertisements. 2023 Torquetenovirus Cognitive impairment Physical frailty Aging Inflammation Torquetenovirus (TTV) is a small, single-stranded circular DNA virus classified into the Anelloviridae family, detectable in various body fluids of healthy individuals [ 1, 2...
Journal Articles
Subject Area:
Topic Article Package: ADC (Antibody-Drug Conjugates)
, Karger e-Journal Backfile Collection 2023
, Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2023) 69 (4): 416–427.
Published Online: 20 April 2023
..., housing, and smoking status, significantly predicting mortality risk. Discussion/Conclusion: The onset and progression of multimorbidity and its mortality impact are driven by systemic factors, including inflammation, metabolic dysfunction (insulin resistance), malnutrition, and frailty. The measurement...
Journal Articles
Yan-Mei Huang, Bing’er Xu, Zheng Kuai, Yu-Ting He, Yi Lu, Ji-Ping Shen, Ke-Fen Wu, Jia-Yu Wu, Wei-Ying Ren, Yu Hu
Journal:
Gerontology
Gerontology (2023) 69 (4): 428–449.
Published Online: 20 April 2023
... as a transmission electron microscope. Serum inflammation marker levels were measured using ELISA. Additionally, anti-oxidative enzymes GPX-4 and SOD-2 and receptors of GLP-2 and vitamin D expression in the ileum and colon were detected under immunofluorescence staining. Results: Six-week GLP-2 treatment attenuated...
Journal Articles
Association among Terminally Differentiated T Cells, Frailty, and Dependency in a Group of Cuban Centenarians
Available to PurchaseAna Laura Añé-Kourí, Nuris Ledón, Mercedes Bárbara Ramos, Amnely González, Karla Pereira, Marbelys Rodríguez, Alejandro Vidal, Yamile Rodríguez, Yamile de la Caridad Bicet, Egda Llanez-Gregorich, Patricia Lorenzo-Luaces, Gisela María Suárez, Alexa Silva, Tania Crombet, Danay Saavedra, Agustin Lage
Journal:
Gerontology
Gerontology (2023) 69 (3): 239–248.
Published Online: 07 March 2023
.... 2022 Centenarians Terminally differentiated T cells Frailty Immunosenescence Inflammation Longevity is a topic of growing interest in medicine, especially given the continuous increase in human extreme longevity. Centenarians are considered a model of successful aging since they have...
Journal Articles
Predictive Ability of Systemic Inflammation Response Index for the Risk of Pneumonia in Patients with Acute Ischemic Stroke
Available to Purchase
Journal:
Gerontology
Gerontology (2023) 69 (2): 181–188.
Published Online: 07 February 2023
...Dan Yan; Caijun Dai; Ruoting Xu; Qiqi Huang; Wenwei Ren Introduction: Several studies have examined the crucial role of inflammatory indexes such as the ratio of monocyte and lymphocyte (MLR), systemic-immune-inflammation-index, and the ratio of neutrophil and lymphocyte (NLR) in stroke-associated...
Journal Articles
Subject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2022) 68 (8): 920–934.
Published Online: 23 August 2022
... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2022 Senolytics Dasatinib Quercetin Senescence Inflammation YTHDF2 Cells were lysed with RIPA (Beyotime...
Journal Articles
Nikolaus Buchmann, Jens Fielitz, Dominik Spira, Maximilian König, Kristina Norman, Graham Pawelec, David Goldeck, Ilja Demuth, Elisabeth Steinhagen-Thiessen
Journal:
Gerontology
Gerontology (2022) 68 (9): 989–998.
Published Online: 31 January 2022
... condition, which may promote and be promoted by inflammation. However, whether inflammation in MetS (metaflammation) is associated with lower muscle mass is still unclear. Methods: Complete cross-sectional data on body composition, MetS, and the inflammatory markers interleukin (IL)-1β, IL-6, IL-10, tumor...
Journal Articles
Influenza A-Associated In-Hospital Mortality in Very Older People: Does Inflammation Also Play a Role?
Available to PurchaseSubject Area:
Geriatrics and Gerontology
Estibaliz Arrieta, Antonio Lalueza, Blanca Ayuso-García, Hernando Trujillo, Dolores Folgueira, Diana Paredes, Miguel Ángel Verdejo, Javier Camacho, José María Caso, Carlos Heredia, Cecilia Cueto-Felgueroso, Daniel Pleguezuelo, Antonio Serrano, Carlos Lumbreras
Journal:
Gerontology
Gerontology (2022) 68 (7): 780–788.
Published Online: 30 September 2021
... was to analyze the clinical manifestations and outcome of the oldest old (people aged ≥85 years) who were admitted to the hospital with a confirmed influenza A virus infection in comparison with younger patients and to assess the role of inflammation in the outcome of influenza infection in this population...
Journal Articles
Multidimensional Prognostic Index Predicts Clinical Outcome and Mortality in Hospitalised Older Patients with Diverticular Disease
Available to PurchaseSubject Area:
Geriatrics and Gerontology
Marco Vincenzo Lenti, Nicola Aronico, Paolo Giuffrida, Stefania Costa, Martina Costetti, Clarissa Musacchio, Luca Pastorelli, Caterina Mengoli, Federica Borrelli de Andreis, Sara Cococcia, Carmine Tinelli, Catherine Klersy, Maurizio Vecchi, Alberto Pilotto, Antonio Di Sabatino
Journal:
Gerontology
Gerontology (2022) 68 (1): 44–52.
Published Online: 13 April 2021
...) and complicated forms (i.e., acute diverticulitis and segmental colitis associated diverticulitis [SCAD]). SCAD was considered a complication of DD according to the Diverticular Inflammation and Complication Assessment [ 15 ], and the diagnosis was made according to endoscopic (i.e., oedema, focal erythema...
Journal Articles
Immunological Implications of Physical Inactivity among Older Adults during the COVID-19 Pandemic
FreeSubject Area:
Topic Article Package: Moksha
, Topic Article Package: Coronavirus (COVID-19)
, Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2020) 66 (5): 431–438.
Published Online: 25 June 2020
... 1. Tay MZ , Poh CM , Rénia L , MacAry PA , Ng LF . The trinity of COVID-19: immunity, inflammation and intervention . Nat Rev Immunol . 2020 Jun ; 20 (6): 363 – 74 . 10.1038/s41577-020-0311-8 32346093 1474-1733 2. Werneck AO , Collings PJ...
Journal Articles
Inflammation and the Alteration of B-Cell Physiology in Aging
Available to PurchaseSubject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2020) 66 (2): 105–113.
Published Online: 25 September 2019
... for the decline in effective immunity is the rise of the systemic levels of pro-inflammatory molecules during aging, establishing a chronic low-grade inflammation. Indeed, numerous alterations affecting directly or indirectly B cells in old people and mice are reminiscent of various effects of acute inflammation...
Journal Articles
In a Nutshell: Findings from the Bruneck Study
Available to PurchaseSubject Area:
Geriatrics and Gerontology
Journal:
Gerontology
Gerontology (2019) 65 (1): 9–19.
Published Online: 04 September 2018
... from any ideas, methods, instructions or products referred to in the content or advertisements. Population study Cohort Cardiovascular disease Stroke Myocardial infraction Atherosclerosis Inflammation Vascular remodeling Innate immunity Aging The Bruneck Study was launched...
Journal Articles
Anti-Inflammatory Nutrition and Successful Ageing in Elderly Individuals: The Multinational MEDIS Study
Available to PurchaseSubject Area:
Geriatrics and Gerontology
Stefanos Tyrovolas, Josep Maria Haro, Alexandra Foscolou, Dimitra Tyrovola, Anargiros Mariolis, Vassiliki Bountziouka, Suzanne Piscopo, Giuseppe Valacchi, Foteini Anastasiou, Efthimios Gotsis, George Metallinos, Natassa Papairakleous, Evangelos Polychronopoulos, Antonia-Leda Matalas, Christos Lionis, Akis Zeimbekis, Josep-Antoni Tur, Labros S. Sidossis, Demosthenes B. Panagiotakos, for the MEDIS Study Group
Journal:
Gerontology
Gerontology (2017) 64 (1): 3–10.
Published Online: 09 September 2017
... Lionis; Akis Zeimbekis; Josep-Antoni Tur; Labros S. Sidossis; Demosthenes B. Panagiotakos; for the MEDIS Study Group Background: The role of diet and inflammation in successful ageing is not transparent, and as such, is still being investigated. The aim of the present work was to evaluate...
Journal Articles
Alterations in Monocyte Phenotypes and Functions after a Hip Fracture in Elderly Individuals: A 6-Month Longitudinal Study
Available to PurchaseSubject Area:
Geriatrics and Gerontology
Sarra Baëhl, Hugo Garneau, Dominique Lorrain, Isabelle Viens, Amy Svotelis, Janet M. Lord, François Cabana, Anis Larbi, Gilles Dupuis, Tamàs Fülöp
Journal:
Gerontology
Gerontology (2016) 62 (5): 477–490.
Published Online: 27 January 2016
... aged 65 and older is a fall that results in a fracture of the hip (HF). HF causes a state of inflammation that may affect immune responses. In this connection, we have reported that HF induced alterations in neutrophil functions. Objective: To assess the impact of HF on classical (cM), intermediate (iM...
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