... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Ageing Faecal microbiota transplantation Immunosenescence Inflammation Renal interstitial fibrosis The elderly population is the main demographic...

.... 2022 Centenarians Terminally differentiated T cells Frailty Immunosenescence Inflammation Longevity is a topic of growing interest in medicine, especially given the continuous increase in human extreme longevity. Centenarians are considered a model of successful aging since they have...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Exercise Ageing Cellular senescence Immunosenescence Immunology Immunosenescence, the gradual remodelling...

..., instructions or products referred to in the content or advertisements. COVID-19 Antibody response Long-term care facilities BNT162b2 Immunosenescence The COVID-19 pandemic has disproportionately affected older people and particularly those living in long-term care facilities (LTCFs...

... Immunosenescence National Institutes of Health (NIH) 10.13039/100000002 Aging is characterized by low-grade chronic inflammation called inflammaging [ 1 ], which represents a significant risk factor for morbidity and mortality of elderly individuals as it is implicated in the pathogenesis...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Cellular senescence Tumorigenesis Immunosenescence Senolytics National Institutes of Health (NIH) 10.13039/100000002 Most spontaneous human malignancies display an increased...

... the innate and the adaptive system. This process is termed immunosenescence or immune dysregulation and, basically, includes 3 events: a reduction in immune response, an increase in the inflammatory and oxidation background (inflammaging and oxi-inflammaging), and a production of autoantibodies. While...

... the innate and adaptive immune system undergoes characteristic changes, collectively termed immunosenescence. With increasing age hematopoietic stem cells differentiate preferentially into myeloid progenitors at the expense of the lymphoid lineage [ 4 ]. Therefore, the number of innate immune cells...

..., termed immunosenescence, and age-related changes in tissue structure influence the development of these disorders. Common complications are comorbidities, polypharmacy, and adverse effects of drugs. The elderly have difficulty mounting protective immune responses against newly encountered antigens...

... implications of immunological immaturity or immunosenescence and its impact on vaccine immunogenicity and efficacy will be highlighted in this review. Several approaches have been undertaken to promote Th1 responses in neonates and to enhance immune functions in elderly, such as conjugation to carrier proteins...

... cellular lifespan. Therefore, telomere dynamics are critical in preserving immune function and have become a focus for studies of immunosenescence and autoimmunity. In this review, we describe the role of telomeric nucleoproteins in shaping telomere architecture and in suppressing DNA damage responses. We...

.... However, age-related changes dramatically affect both the innate as well as the adaptive immune system – a phenomenon known as immunosenescence. Deficiencies in micronutrients, especially zinc and iron, as well as vitamin D, in the elderly may also contribute to the development of allergies. A further...

..., instructions or products referred to in the content or advertisements. Exercise Immunosenescence Telomeres Immune risk profile Cytomegalovirus Physical activity Clinical Section / Mini-Review Gerontology 2010;56:449 458 DOI: 10.1159/000270905 Received: May 14, 2009 Accepted: May 14, 2009...

... or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. CD4+ cells Immunosenescence...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Immunosenescence Immunoregulation Mononuclear phagocytes Cytokines Cell adhesion molecules Experimental Section Gerontology 1993:39:93-108...

... Immunosenescence Experimental Section Gerontology 1993;39:19-27 Zenghua Liao John H. Tu Catherine B. Small Steven M. Schnippet' David L. Rosenstreich Departments of Medicine, and Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, N.Y., USA KeyWords Interleukin-1 Aging Immunosenescence...

... and Laboratory o f Experimental Medicine, Centre Hospitalier Universitaire de Montigny-le-Tillcul, Université Libre de Bruxelles, Belgium Key Words. Immunosenescence Immune deficiency Vitamin C Cell-mediated immunity Abstract. Both ageing and vitamin C (VC) deficiency result in immune defect. Since low...

... levels. Immunity Infection Immunosenescence © 1984 S. Karger AG, Basel 1984 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical...

... be playing an important role in the resistance against life-shortening malignant lymphoma in C57BL/6 mice. 12 01 1984 8 02 1984 6 4 2009 Mice Immunosenescence Life span Tumor incidence Gerontology 30: 223-233 (1984) © 1984 S. Karger AG. Basel 0304-324X/84/0304-0223$2.75/0...

... cells, after adjustment for age, correlates with increased mortality. 21 08 2008 5 11 2008 4 2 2009 Naïve T cells Memory T cells Immunosenescence Mortality Experimental Section Gerontology 2009;55:314 321 DOI: 10.1159/000199451 Received: August 21, 2008 Accepted: November 5...