... secretory phenotype (SASP), which are thought to contribute to the functional decline of the skin as a consequence of aging. Due to the potential negative effects of the SASP in aged organisms, drugs that selectively target senescent cells represent an intriguing therapeutic strategy to delay aging and age...

...L.B. Sourander A good pharmacological treatment of urinary incontinence must be based on an appropriate understanding of the underlying physiological disturbance and on a basic knowledge of drugs, their mode of action on the urinary tract and their side effects. A general drug treatment policy must...

... important reason. In a representative survey performed in Austria, 64% of the respondents of the age group 60–69 reported drug treatment, 19% a medically caused dietary regimen. Older patients very often take different drugs on a regular basis, this is one of the reasons for possible noncompliance or other...

...H.B. Stähelin The prescription of drugs is the first step towards the factual realization of a therapeutic goal. In order to arrive at this step the physician deals with three conceptually distinguishable levels of decisions: The first comprises the evaluation of physical and mental health...

...Leigh Atkinson; Iris Gibson; James Andrews An investigation was made by an Occupational Therapist into the problems encountered by 50 elderly patients in the self-administration of drugs prior to discharge home. The questions asked the patients are enumerated and recommendations are made concerning...

... including dyskinesia. Trials with selegiline as adjuvant therapy were less rigorous but it can allow a reduction in levodopa dose and motor impairments. No studies have compared these three classes of drug as adjuvant therapy so there is no evidence on which to base rational decisions in this type...

...W. Mühlberg; D. Platt About 40% of the intoxications after drug administration occur in the elderly. A significant proportion of the disease states in elderly patients is related to adverse reactions to prescribed drugs. Declining renal function, a reduction in both renal blood flow and glomerular...