.... It also provides insights from a drug discovery perspective into the druggability, therapeutic strategies, and challenges to target CD33 for treating this devastating disorder. [email protected] 10 04 2018 1 08 2018 12 12 2018 Additionally, a recent study showed...

.... Aging Frailty Skeletal muscle Atrophy Growth and differentiation factor Drug discovery Obesity Diabetes Humans achieve peak skeletal muscle mass in mid-life and then experience a progressive decline that can equal 50% by the ninth decade. The significant loss of skeletal muscle mass...

... be superior to lifespan studies for initial screening of candidate longevity therapeutics. Caloric restriction mimetics Insulin/IGF-I signaling Drug development Drug discovery Lifespan Microarray 22 02 2007 28 03 2007 15 6 2007 © 2007 S. Karger AG, Basel 2007 Copyright...