...Nienke Legdeur; Maryam Badissi; Vikram Venkatraghavan; Davis C. Woodworth; Fanny Orlhac; Jean-Sébastien Vidal; Frederik Barkhof; Claudia H. Kawas; Pieter Jelle Visser; María M. Corrada; Majon Muller; Hanneke F.M. Rhodius-Meester Introduction: Physical function and cognition seem to be interrelated...

...Paul W. Kline; Faisal D. Shaikh; Jaclyn E. Tennant; Renee Hamel; Lisa A. Zukowski Introduction: The purpose of this study was to determine if demographic variables and measures of cognitive function, functional mobility, self-reported balance self-efficacy, and self-reported physical activity can...

... (AV) technology is unknown. The aim was to evaluate safety and cognitive workload while operating AV technology in drivers with preclinical AD. Introduction: This cross-sectional study included 40 participants: 19 older adults (age 74.16 ± 4.78; MOCA scores 26.42 ± 2.52) with preclinical AD, evidenced...

... between occupational mental demands and late-life cognition are poorly understood. The objective of this study was to assess whether the association between occupational complexity and cognition is related to and moderated by brain integrity in individuals at risk for dementia. Brain integrity...

.... Ploubidis; Marcus Richards; Praveetha Patalay; on behalf of the SHARED Consortium Introduction: In this study, we examine whether social health markers measured at baseline are associated with differences in cognitive capability and the rate of cognitive decline over an 11-to-18-year period among older...

...; Jenny T. van der Steen; Carolien Smits; René Melis; Marcel Olde Rikkert The concept of resilience, i.e., the capacity of a system to bounce back after a stressor, is gaining interest across many fields of science, policy, and practice. To date, resilience research in people with cognitive decline has...

...Yuying Sun; Zhihui Wang; Shengzhi Sun; Lu Cui; Xiaoquan Zhu; Sai Yin Ho; Shige Qi Introduction: Cognitive stimulating activities and a healthy lifestyle are associated with less cognitive impairment. However, whether the association is varied by Apolipoprotein epsilon 4 (APOE ε4) allele carrier...

...Allison A.M. Bielak; Alan J. Gow Activity engagement is a modifiable factor that has been widely-cited as being good for the aging brain and cognition and represents a valuable target for reducing dementia risk. However, specific issues about activity engagement (mental, social, and physical...

...Douglas William Hanes; Sean A.P. Clouston Introduction: The ongoing marginalization of lesbian, gay, and bisexual people has been hypothesized to produce poorer late-in-life cognitive outcomes, according to mechanisms posited by minority stress and allostatic load theories. Yet the existence...

...Shawna Hopper; Nicole G. Hammond; Vanessa Taler; Arne Stinchcombe Introduction: Subjective cognitive decline (SCD), a self-reported decline in cognition in otherwise cognitively healthy people, has been acknowledged as a risk factor for Alzheimer’s disease. Using data from the Canadian Longitudinal...

... hypotension were excluded. Assessments of motor, visual, and cognitive functions were carried out during visits at baseline. Between visits at 12 and 24 months of follow-up, data were collected by phone call every 2 months (falls, traumatic falls, hospitalizations, cognitive fluctuations, delirium...

...), whereas it was not significantly associated with cognitive decline, depressive symptoms, and social support. Conclusion: Our findings stress the importance of gender, age, widowhood, and functional decline for institutionalization among the oldest old. Preventing or at least postponing functional decline...

.... However, MCIDs of many cognitive measures are not established. We aimed to determine MCIDs of the Digit Symbol Substitution Test ([DSST] processing speed measure), Stroop (inhibition measure), and Trail Making Test B-A (TMT; set-shifting measure), using anchor- and distribution-based approaches in older...

...Stacy L. Andersen; Mengtian Du; Stephanie Cosentino; Nicole Schupf; Andrea L. Rosso; Thomas T. Perls; Paola Sebastiani; the Long Life Family Study Introduction: Cross-sectional analyses have associated familial longevity with better cognitive function and lower risk of cognitive impairment...

...Ram kinker Mishra; Catherine Park; He Zhou; Bijan Najafi; T. Adam Thrasher Introduction: Parkinson’s disease (PD) progressively impairs motor and cognitive performance. The current tools to detect decline in motor and cognitive functioning are often impractical for busy clinics and home settings...

...Katherine E. Dorociak; Nora Mattek; Jonathan Lee; Mira I Leese; Nicole Bouranis; Danish Imtiaz; Bridget M. Doane; John P.K. Bernstein; Jeffrey A. Kaye; Adriana M. Hughes Introduction: Brief, Web-based, and self-administered cognitive assessments hold promise for early detection of cognitive decline...

... studies should recruit larger samples and collect sensor-measured driving data over a more extended time frame to better determine how and why these self-regulation changes take place. Driving Cognition Self-regulation National Institutes of Health (NIH) 10.13039/100000002 From...

... prevention, we aimed to identify baseline cognitive and mobility factors that predict adherence to the Otago Exercise Program (OEP) – a home-based exercise program proven to prevent falls. Methods: We conducted a secondary longitudinal analysis of data from a randomized clinical trial (RCT) (OEP compared...

...Laura Zamarian; Lukas Lenhart; Melanie Nagele; Ruth Steiger; Elke Ruth Gizewski; Thomas Benke; Christoph Scherfler; Margarete Delazer Introduction: Previous studies have shown an association between a high health numeracy and good cognitive functioning. Objective: To investigate the moderation...

...Anna Cornelia Maria Bauer; Gerda Andringa The number of elderly is growing rapidly, including those that struggle with cognitive decline and, consequently, activities of daily living. Developing interventions that slow down cognitive decline would greatly benefit the autonomy of these elderly...