..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Aging Regeneration Axolotl Cancer Scar formation Immune system Nerve...

... the current status of research on miR-17-5p with emphasis on its role in cellular senescence, aging and cancer, which points to a pleiotropic function of miR-17-5p regulating multiple targets involved in autophagy, cell cycle regulation and apoptosis in a tissue-dependent fashion. In addition, its elevated...

...Michael Schwenk; Gurtej S. Grewal; Dustin Holloway; Amy Muchna; Linda Garland; Bijan Najafi Background: Cancer patients with chemotherapy-induced peripheral neuropathy (CIPN) have deficits in sensory and motor skills leading to inappropriate proprioceptive feedback, impaired postural control...

...-driven breast cancer. This review will highlight some of the functions of RANKL-RANK in bone turnover, the immune system and brain with a focus on the regulatory role of the female sex hormones. 5 08 2014 5 01 2015 14 02 2015 © 2015 S. Karger AG, Basel Copyright / Drug Dosage...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Vitamin E Osteoporosis Cardiovascular disease Cancer Dementia Diseases associated with aging are dramatically increasing due to the worldwide expansion...

... patients that have neither WRN nor LMNA mutations. Efforts are underway to identify the responsible genes for AWS with unknown genetic causes. While WS and AWS are rare disorders, the causative genes have been shown to have much wider implications for cancer, cardiovascular disease and the biology of aging...

... from any ideas, methods, instructions or products referred to in the content or advertisements. Ageing Apolipoprotein J/Clusterin Cancer Chaperone Free radicals Inflammation Neurodegeneration Oxidative stress Oxygen is essential to support aerobic metabolism and life...

... exclusively derived from the paternal allele. Loss of imprinting of the IGF2 gene is a recurrent observation in growth disorders that combine overgrowth with a variety of malignant tumours. Moreover, IGF2 has been proposed to play a role in the development of a variety of seemingly unrelated cancers that play...

... by the hormone adiponectin in CR and long-lived dwarf mice can lower endogenous glucose production and raise fatty acid oxidation. Adiponectin reduction of plasma glucose in CR and long-lived dwarf mice can thereby lower age-related increases in oxidative damage and cancer. Experimental Section / Viewpoint...

...% confidence interval 1.109–1.491, p = 0.031) after adjusting for covariates. The high risk of mortality in the hyper-IgA group was significant in males, but not in females. Moreover, Kaplan-Meier analysis revealed that IgA was related to cancer mortality in males (log rank, p = 0.031), but not to pneumonia...

... followed by declines. Death rates from cancer and the percent of deaths attributed to cancer have increased during 1950–1990. Conclusions: The above changes coincide with major changes in medical science and care, the identification of the risk factors predisposing to ischemic heart disease...