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Keywords: Apoptosis
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Journal Articles
Journal: Gerontology
Gerontology (2022) 68 (4): 431–441.
Published Online: 03 May 2022
... of miR-3622b-5p and circCCDC66 in OA cartilage tissues were detected by qRT-PCR. Cell Counting Kit-8 (CCK8) and flow cytometry were used to detect the chondrocyte viability and apoptosis. The expression of chondrocyte inflammatory factors (IL-6 and TNF-α) was measured by ELISA. The target genes...
Journal Articles
Journal: Gerontology
Gerontology (2016) 62 (2): 173–181.
Published Online: 03 July 2015
.... Initially identified as an inhibitor of apoptosis protein, it also plays a major role in the regulation of cell division. As such, it acts as a subunit of the chromosomal passenger complex, composed of the mitotic kinase aurora B, borealin and inner centromere protein, and is essential for proper chromosome...
Journal Articles
Journal: Gerontology
Gerontology (2015) 61 (5): 416–426.
Published Online: 03 December 2014
... is modified by age, which in turn may affect disease outcome in the elderly. In this review, we discuss the effect of age on VSMC behaviour, proliferation, migration, apoptosis, inflammation, extracellular matrix synthesis and calcification. In addition, we discuss the multiple signalling factors underlying...
Journal Articles
Journal: Gerontology
Gerontology (2013) 59 (5): 413–420.
Published Online: 18 April 2013
... after birth due to brain hypoplasia with apoptosis. There was a clear increase in TdT-mediated dUTP nick end labeling (TUNEL)-positive neuronal cells, an indicator of apoptosis, in particular in the deep cortex layers. Embryonic fibroblasts and embryonic stem cells from these mice revealed that Drp1...
Journal Articles
Journal Articles
Journal: Gerontology
Gerontology (2011) 57 (6): 521–527.
Published Online: 15 December 2010
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Apoptosis Cell death Fluorescence Fruit Musa acuminata Senescence Experimental Section / Mini-Review Gerontology 2011;57:521 527 DOI...
Journal Articles
Journal: Gerontology
Gerontology (1997) 43 (Suppl. 1): 35–42.
Published Online: 15 April 2009
...Keisuke Fukuo; Takeshi Nakahashi; Shintaro Nomura; Shigeki Hata; Toshimitsu Suhara; Masumi Shimizu; Michio Tamatani; Shigeto Morimoto; Yukihiko Kitamura; Toshio Ogihara Apoptosis is a programmed cell death that plays a major role during development, homeostasis, and in many diseases. Recent...
Journal Articles
Journal: Gerontology
Gerontology (2006) 53 (1): 52–60.
Published Online: 10 October 2006
... accumulates amyloid protein in the parenchyma and changes the properties of secretory granules of the acinar cells in the serous demilune with aging, though apoptosis of the parenchymal cells and the decrease of the gland weight are slight. 1 07 2006 8 08 2006 10 10 2006 © 2007 S. Karger...
Journal Articles
Journal: Gerontology
Gerontology (2002) 48 (5): 282–288.
Published Online: 16 August 2002
.... The statistical relationship is supported by the physiological relationship between TGF-β1, IL-2, apoptosis, and aging. Conclusion: The results suggest a reduction in SWS flow in association with an increase of salivary TGF-β1 concentrations. This reduction concurs with the histomorphometric investigations, which...
Journal Articles
Journal: Gerontology
Gerontology (2002) 48 (4): 204–208.
Published Online: 12 June 2002
...: The balance between enterocyte apoptosis and proliferation being responsible for the maintenance of tissue size, mucosal morphology and function in the gastrointestinal tract, the aim of our study was to evaluate the rates of enterocyte apoptosis and proliferation in the duodenal mucosa of aged human beings...
Journal Articles
Journal: Gerontology
Gerontology (2002) 48 (3): 179–184.
Published Online: 15 April 2002
... physiological autoimmunity and autoimmune diseases. Nevertheless, physiological autoimmunity seems to be directed mostly by natural factors (such as aging and apoptosis) but primary autoimmune diseases may be caused by genetic instability that is enhanced by aging as well. 15 4 2002 © 2002 S. Karger...
Journal Articles
Journal: Gerontology
Gerontology (2002) 48 (2): 62–71.
Published Online: 27 February 2002
... and cell-cell interactions with a unique pathophysiology. In this review, we describe the cellular and metabolic changes associated with aging bone and present recent evidence regarding cell differentiation within the bone marrow. We also consider the mechanism of programmed cell death, apoptosis, as being...