.... Objectives: We aimed to clarify this association using meta-analysis. Methods: We systematically searched the PubMed, Embase, and Web of Science databases up to December 2022 for relevant studies that investigated the association between MCR and incident all-cause dementia and Alzheimer’s disease (AD...

...Mustafa Gokce; Halil Aziz Velioglu; Muhammed Yunus Bektay; Eray Metin Guler Introduction: Alzheimer’s disease (AD) is one of the pathologies that the scientific world is still desperate for. The aim of this study was the investigation of diazepam binding inhibitor (DBI) as a prognostic factor...

...Pedram Ahmadnezhad; Jeffrey M. Burns; Abiodun E. Akinwuntan; Maud Ranchet; Alexandra Kondyli; Jonathan D. Mahnken; Hannes Devos Introduction: Older adults with preclinical Alzheimer’s disease (AD) show changes in on-road driving performance. The impact of preclinical AD on using automated vehicle...

... sample – MRI ( N = 126), PiB-PET ( N = 41) – were included in a post hoc cross-sectional analysis. Neuroimaging parameters comprised the Alzheimer’s disease signature (ADS) cortical thickness (FreeSurfer 5.3), medial temporal atrophy (MTA), and amyloid accumulation (PiB-PET). Cognition was assessed using...

...Shiliang Ji; Yijie Wu; Ruifang Zhu; Dongkai Guo; Yiguo Jiang; Lifeng Huang; Xinwei Ma; Liqiang Yu Introduction: Alzheimer’s disease (AD) is a major public health concern worldwide, but there are still no drugs available that treat it effectively. Previous studies have shown that phenylethanoid...

... of those outcomes remains understudied, and results of existing studies have been contradictory. Using a population-based longitudinal aging study, this paper will compare age at diagnosis of Alzheimer’s disease (AD) or a related dementia and rates of cognitive decline between participants in same-sex...

...Xuezhi Zhang; Wenwen Yu; Xuelei Cao; Yongbin Wang; Chao Zhu; Jialiang Guan Aim: The aim of this study is to identify potential serum biomarkers of Alzheimer’s disease (AD) for early diagnosis and to evaluate these markers on a large cohort. Methods: We performed two-dimensional difference gel...

..., instructions or products referred to in the content or advertisements. Cognitive frailty Gait Dual-task walking Older adults Wearable Digital biomarker Digital health Dementia Alzheimer’s disease Cognitive decline Cognitive motoric syndrome Dementia causes great stress to our society...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Alzheimer’s disease Air pollution Cognitive deterioration Sulfur dioxide Ozone Alzheimer’s disease (AD...

... participated in this study; 36 with cognitive impairment due to Alzheimer’s disease (AD), 30 with dementia with Lewy bodies (DLB), 16 with Parkinson’s disease dementia (PDD), and 26 controls. A tri-axial accelerometer recorded continuous data of volume, variability, and pattern of HA over 7 days. Participants...

... isoform specificity. Ageing Alzheimer’s disease Huntington’s disease Neurodegeneration Neuron Parkinson’s disease SUMO Posttranslational modifications are key regulators of cellular processes under normal, stress and disease conditions. These modifications provide the means to a fast...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. [email protected] 19 12 2018 1 04 2019 20 5 2019 Virtual reality Dementia Mild cognitive impairment Alzheimer’s disease Feasibility...

.... Middeldorp J, Lehallier B, Villeda SA, Miedema SS, Evans E, Czirr E, Zhang H, Luo J, Stan T, Mosher KI, Masliah E, Wyss-Coray T: Preclinical assessment of young blood plasma for Alzheimer disease. JAMA Neurol 2016; 73: 1325–1333. 27. Xiang Y, Bu XL, Liu YH, Zhu C, Shen LL, Jiao SS, Zhu XY, Giunta B, Tan...

...Lingzhi Zhao Alzheimer’s disease (AD) affects nearly 50 million people worldwide, and currently no disease-modifying treatment is available. With continuous failure of anti-amyloid-beta- or tau-based therapies, identification of new targets has become an urgent necessity for AD prevention...

...Candice E. Van Skike; Veronica Galvan Cerebrovascular dysfunction is detected prior to the onset of cognitive and histopathological changes in Alzheimer's disease (AD). Increasing evidence indicates a critical role of cerebrovascular dysfunction in the initiation and progression of AD. Recent...

... with Alzheimer disease (AD), were recruited. Subjects completed iTMT, using a wearable sensor attached to the leg, which translates the motion of the ankle into a human-machine interface. iTMT tests included reaching to 5 indexed circles on a computer screen by moving the ankle-joint while standing. iTMT...

...: A uniformed data set was administered in Taiwan, China, Hong Kong, Korea, Japan, Philippines, Thailand, Singapore, and Indonesia to gather data with regard to Alzheimer's disease (AD) and its related issues for these countries. Results: In total, 2,370 AD patients and their caregivers were recruited from 2011...

...Jewel Yi; Hoe Chung-Yeung Lee; Richard Parsons; Torbjorn Falkmer Introduction: The initial symptoms of Alzheimer's disease (AD) include attention deficits, memory loss and deficiencies in topographic and spatial orientation. People with AD may have way-finding difficulties in driving due...

... for patients with mild cognitive impairment (MCI) and early-stage Alzheimer's disease (AD) and compares them to healthy subjects. Methods: A new test was specifically designed for this study and presented to 10 patients with MCI diagnosis, 10 with AD diagnosis and 23 controls. The test comprised musical...

...Allal Boutajangout; Thomas Wisniewski The accumulation of aggregated, hyperphosphorylated tau as neurofibrillary tangles and neuropil threads are cardinal features of Alzheimer's disease (AD). The other lesions found in AD include amyloid plaques and congophilic amyloid angiopathy, both associated...