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Keywords: Alzheimer’s diseaseClose
Gerontology (2023) 69 (9): 1104–1112.
Published Online: 22 August 2023
...Mustafa Gokce; Halil Aziz Velioglu; Muhammed Yunus Bektay; Eray Metin Guler Introduction: Alzheimer’s disease (AD) is one of the pathologies that the scientific world is still desperate for. The aim of this study was the investigation of diazepam binding inhibitor (DBI) as a prognostic factor...
Pedram Ahmadnezhad, Jeffrey M. Burns, Abiodun E. Akinwuntan, Maud Ranchet, Alexandra Kondyli, Jonathan D. Mahnken, Hannes Devos
Gerontology (2023) 69 (11): 1307–1314.
Published Online: 09 August 2023
...Pedram Ahmadnezhad; Jeffrey M. Burns; Abiodun E. Akinwuntan; Maud Ranchet; Alexandra Kondyli; Jonathan D. Mahnken; Hannes Devos Introduction: Older adults with preclinical Alzheimer’s disease (AD) show changes in on-road driving performance. The impact of preclinical AD on using automated vehicle...
Anders Rydström, Ruth Stephen, Ingemar Kåreholt, Alexander Darin Mattsson, Tiia Ngandu, Jenni Lehtisalo, Lars Bäckman, Nina Kemppainen, Juha Rinne, Shireen Sindi, Hilkka Soininen, Ritva Vanninen, Alina Solomon, Francesca Mangialasche
Gerontology (2023) 69 (8): 972–985.
Published Online: 08 August 2023
... sample – MRI ( N = 126), PiB-PET ( N = 41) – were included in a post hoc cross-sectional analysis. Neuroimaging parameters comprised the Alzheimer’s disease signature (ADS) cortical thickness (FreeSurfer 5.3), medial temporal atrophy (MTA), and amyloid accumulation (PiB-PET). Cognition was assessed using...
Gerontology (2023) 69 (9): 1065–1075.
Published Online: 07 June 2023
...Shiliang Ji; Yijie Wu; Ruifang Zhu; Dongkai Guo; Yiguo Jiang; Lifeng Huang; Xinwei Ma; Liqiang Yu Introduction: Alzheimer’s disease (AD) is a major public health concern worldwide, but there are still no drugs available that treat it effectively. Previous studies have shown that phenylethanoid...
Gerontology (2023) 69 (3): 356–369.
Published Online: 07 March 2023
... of those outcomes remains understudied, and results of existing studies have been contradictory. Using a population-based longitudinal aging study, this paper will compare age at diagnosis of Alzheimer’s disease (AD) or a related dementia and rates of cognitive decline between participants in same-sex...
Gerontology (2022) 68 (6): 686–698.
Published Online: 07 June 2022
...Xuezhi Zhang; Wenwen Yu; Xuelei Cao; Yongbin Wang; Chao Zhu; Jialiang Guan Aim: The aim of this study is to identify potential serum biomarkers of Alzheimer’s disease (AD) for early diagnosis and to evaluate these markers on a large cohort. Methods: We performed two-dimensional difference gel...
He Zhou, Catherine Park, Mohammad Shahbazi, Michele K. York, Mark E. Kunik, Aanand D. Naik, Bijan Najafi
Gerontology (2022) 68 (2): 224–233.
Published Online: 10 May 2021
..., instructions or products referred to in the content or advertisements. Cognitive frailty Gait Dual-task walking Older adults Wearable Digital biomarker Digital health Dementia Alzheimer’s disease Cognitive decline Cognitive motoric syndrome Dementia causes great stress to our society...
Gerontology (2022) 68 (1): 53–61.
Published Online: 21 April 2021
...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Alzheimer’s disease Air pollution Cognitive deterioration Sulfur dioxide Ozone Alzheimer’s disease (AD...
Gerontology (2020) 66 (2): 197–208.
Published Online: 18 September 2019
... participated in this study; 36 with cognitive impairment due to Alzheimer’s disease (AD), 30 with dementia with Lewy bodies (DLB), 16 with Parkinson’s disease dementia (PDD), and 26 controls. A tri-axial accelerometer recorded continuous data of volume, variability, and pattern of HA over 7 days. Participants...
Gerontology (2020) 66 (2): 122–130.
Published Online: 10 September 2019
... at synapses . Front Cell Neurosci . 2018 May ; 12 : 117 . 10.3389/fncel.2018.00117 29766991 1662-5102 33. Spires-Jones TL , Hyman BT . The intersection of amyloid beta and tau at synapses in Alzheimer’s disease . Neuron . 2014 May ; 82 ( 4 ): 756 – 71 . 10.1016/j.neuron...
Nathan M. D’Cunha, Dung Nguyen, Nenad Naumovski, Andrew J. McKune, Jane Kellett, Ekavi N. Georgousopoulou, Jane Frost, Stephen Isbel
Gerontology (2019) 65 (4): 430–440.
Published Online: 20 May 2019
..., Chapoulie E, Manera V, Chaurasia G, et al. Is it possible to use highly realistic virtual reality in the elderly? A feasibility study with image-based rendering. Neuropsychiatr Dis Treat. 2015 Mar;11:557 63. 15 Aruanno B, Garzotto F. MemHolo: mixed reality experiences for subjects with Alzheimer's disease...
Gerontology (2019) 65 (1): 84–89.
Published Online: 17 January 2019
... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2018 Young blood Young plasma Parabiosis Aging Alzheimer’s disease...
Gerontology (2019) 65 (4): 323–331.
Published Online: 12 December 2018
...Lingzhi Zhao Alzheimer’s disease (AD) affects nearly 50 million people worldwide, and currently no disease-modifying treatment is available. With continuous failure of anti-amyloid-beta- or tau-based therapies, identification of new targets has become an urgent necessity for AD prevention...
Gerontology (2018) 64 (3): 205–211.
Published Online: 11 January 2018
...Candice E. Van Skike; Veronica Galvan Cerebrovascular dysfunction is detected prior to the onset of cognitive and histopathological changes in Alzheimer's disease (AD). Increasing evidence indicates a critical role of cerebrovascular dysfunction in the initiation and progression of AD. Recent...
Gerontology (2017) 63 (2): 189–200.
Published Online: 18 November 2016
... with Alzheimer disease (AD), were recruited. Subjects completed iTMT, using a wearable sensor attached to the leg, which translates the motion of the ankle into a human-machine interface. iTMT tests included reaching to 5 indexed circles on a computer screen by moving the ankle-joint while standing. iTMT...
Yuan-Han Yang, Kenichi Meguro, Sang-Yun Kim, Yong-Soo Shim, Xin Yu, Christopher Li-Hsian Chen, Huali Wang, Linda Lam, Vorapun Senanarong, Jacqueline Dominguez, Pei-yuan Lu, Yu-Te Lin, Chaur-Jong Hu, Pai-Yi Chiu, Jong-Ling Fuh, Wen-Fu Wang, Bao-Cheng Yu, Tao Li, Ming-Wei Wang, Rocksy Fransisca V. Situmeang, Jae-Won Jang, Jing Zhang, Wai-Chi Chan, Yu-Ying Zhou, Hui-ling Lou, Li Zhang, Min Ye, Xu Chen
Gerontology (2016) 62 (4): 425–433.
Published Online: 02 February 2016
...: A uniformed data set was administered in Taiwan, China, Hong Kong, Korea, Japan, Philippines, Thailand, Singapore, and Indonesia to gather data with regard to Alzheimer's disease (AD) and its related issues for these countries. Results: In total, 2,370 AD patients and their caregivers were recruited from 2011...
Gerontology (2014) 61 (1): 79–88.
Published Online: 22 October 2014
...Jewel Yi; Hoe Chung-Yeung Lee; Richard Parsons; Torbjorn Falkmer Introduction: The initial symptoms of Alzheimer's disease (AD) include attention deficits, memory loss and deficiencies in topographic and spatial orientation. People with AD may have way-finding difficulties in driving due...
Manuela Kerer, Josef Marksteiner, Hartmann Hinterhuber, Georg Kemmler, Harald R. Bliem, Elisabeth M. Weiss
Gerontology (2014) 60 (5): 402–412.
Published Online: 09 May 2014
... for patients with mild cognitive impairment (MCI) and early-stage Alzheimer's disease (AD) and compares them to healthy subjects. Methods: A new test was specifically designed for this study and presented to 10 patients with MCI diagnosis, 10 with AD diagnosis and 23 controls. The test comprised musical...
Gerontology (2014) 60 (5): 381–385.
Published Online: 08 April 2014
...Allal Boutajangout; Thomas Wisniewski The accumulation of aggregated, hyperphosphorylated tau as neurofibrillary tangles and neuropil threads are cardinal features of Alzheimer's disease (AD). The other lesions found in AD include amyloid plaques and congophilic amyloid angiopathy, both associated...
James Yungjen Tung, Rhiannon Victoria Rose, Emnet Gammada, Isabel Lam, Eric Alexander Roy, Sandra E. Black, Pascal Poupart
Gerontology (2014) 60 (2): 154–162.
Published Online: 12 December 2013
... as the geographical area a person covers in daily life. Typically measured through questionnaires, life space can be challenging to assess in amnestic dementia associated with Alzheimer's disease (AD). While global positioning system (GPS) technology has been suggested as a potential solution, there remains a lack...