...Ryong-Woon Shin Since the first reports of aluminum-induced neurofibrillary degeneration in experimental animals, extensive studies have been performed to clarify the role played by aluminum in the pathogenesis of Alzheimer’s disease (AD). Additional evidence implicating aluminum in AD includes...

... to 6 months. To establish the relevance of this long-term culture to aging and neurodegenerative diseases, effects of long-term exposure to aluminum, a risk factor for Alzheimer’s disease, on the cultured cortical neurons were investigated. It appeared that aluminium promoted the aggregation of amyloid...

.... Experimental neurofibrillary changes were produced in the rabbit brain by aluminum injection, and the proliferated neurofilaments in the rabbit brain were compared with those in the hamster brain inoculated with Alzheimer buffy coat. The results indicate that the long pathological process in the hamster brain...

...Harold R. Massie; Trevor R. Williams; Valerie R. Aiello Aluminum concentrations in the whole organism increased during development and aging of Drosophila melanogaster . The amount of aluminum in the flies was also reflected by the dietary content of aluminum. Additional dietary aluminum...