...Jiali Wu; Yuxin Jiang; Junran Sun; Xiaodong Sun Introduction: Neovascular age-related macular degeneration (NVAMD) is a leading cause of severe vision impairment in the elderly. Aging is one of the most pivotal underlying molecular mechanisms of NVAMD. Methods: In this study, we identified...

...Yuye Wang; Yifan Zhong; Liang Zhang; Qijun Wu; Yihchung Tham; Tyler Hyungtaek Rim; David Mutugi Kithinji; Jingyang Wu; Chingyu Cheng; Huiying Liang; Honghua Yu; Xiaohong Yang; Lei Liu Objective: Age-related macular degeneration(AMD) has become a major cause of visual impairment worldwide...

...Brad P. Barnett; James T. Handa Background: Age-related macular degeneration (AMD) is the leading cause of blindness in the western world. To prevent what will certainly be a tremendous health and economic burden, effective therapeutics for AMD are urgently needed. To develop these agents...

... macular degeneration. 15 4 2009 Age-related macular degeneration cell culture lipofuscin lysosomes oxygen radicals photo-oxidation retinal pigment epithelium. © 1995 S. Karger AG, Basel 1995 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

...Thuan Quoc Pham; Annette Kifley; Paul Mitchell; Jie Jin Wang Background: The aetiology of age-related macular degeneration (AMD) and cognitive impairment is poorly understood. A link between cognitive impairment and AMD has been proposed although only a weak association was found in population...

...Patricia T. Harvey Of the 38 million people who are blind, the majority, 22 million, are 60 years of age or older. The most common causes of vision loss in elderly people are age-related macular degeneration (AMD), cataract, glaucoma, and diabetic retinopathy. Of these, AMD is the leading cause...