Background: There is evidence for specific age-related deficits in tasks of verbal fluency. Objective: The aim of the present study was to evaluate training and transfer effects after 3 weeks of telephone-based verbal fluency training in old age. Methods: Participants were assigned to one of three training groups, an active control group, or a no-contact control group. Training consisted of 15 sessions of 6 min each over a period of 3 weeks. For the training tasks, different versions of the verbal fluency task were used, each targeting a specific underlying cognitive process (i.e., processing speed, shifting, or inhibition). To measure transfer effects, a neuropsychological test battery including Digit Symbol Substitution, Trail Making, Go/No-Go, Digit Span, N-Back, and a verbal learning and memory test was administered before and after training. Results: Our findings revealed training gains for initial letter fluency training and phonemic switching training, but not for excluded letter fluency training. Moreover, after initial letter fluency training and phonemic switching training, transfer to other verbal fluency tasks was found. In addition, phonemic switching training led to improvement in an untrained short-term memory task. Conclusion: The findings demonstrate that a telephone-based cognitive intervention of overall 90 min significantly improved cognitive performance in healthy older adults above and beyond the improvements in the active control group. The findings provide the basis for cognitive interventions that could easily be integrated into everyday lifestyles and are still targeting specific cognitive functions.

1.
Kempler D, Teng EL, Dick M, Taussig IM, Davis DS: The effects of age, education, and ethnicity on verbal fluency. J Int Neuropsychol Soc 1998;4:531–538.
2.
Monsch AU, Bondi MW, Butters N, Salmon DP, Katzman R, Thal LJ: Comparisons of verbal fluency tasks in the detection of dementia of the Alzheimer type. Arch Neurol 1992;49:1253–1258.
3.
Fisk JE, Sharp CA: Age-related impairment in executive functioning: updating, inhibition, shifting, and access. J Clin Exp Neuropsychol 2004;26:874–890.
4.
Wierenga CE, Benjamin M, Gopinath K, Perlstein WM, Leonard CM, Rothi LJ, Conway T, Cato MA, Briggs R, Crosson B: Age-related changes in word retrieval: role of bilateral frontal and subcortical networks. Neurobiol Aging 2008;29:436–451.
5.
Hultsch DF, Hertzog C, Small BJ, McDonald-Miszczak L, Dixon RA: Short-term longitudinal change in cognitive performance in later life. Psychol Aging 1992;7:571–584.
6.
Tombaugh TN, Kozak J, Rees L: Normative data stratified by age and education for two measures of verbal fluency: Fas and animal naming. Arch Clin Neuropsychol 1999;14:167–177.
7.
Troyer AK, Moscovitch M, Winocur G: Clustering and switching as two components of verbal fluency: evidence from younger and older healthy adults. Neuropsychology 1997;11:138–146.
8.
Brickman AM, Paul RH, Cohen RA, Williams LM, MacGregor KL, Jefferson AL, Tate DF, Gunstad J, Gordon E: Category and letter verbal fluency across the adult lifespan: relationship to EEG theta power. Arch Clin Neuropsychol 2005;20:561–573.
9.
Phillips LH: Age and individual differences in letter fluency. Dev Neuropsychol 1999;15:249–267.
10.
Bryan J, Luszcz MA, Crawford JR: Verbal knowledge and speed of information processing as mediators of age differences in verbal fluency performance among older adults. Psychol Aging 1997;12:473–478.
11.
Rosen VM, Engle RW: The role of working memory capacity in retrieval. J Exp Psychol Gen 1997;126:211–227.
12.
Salthouse TA: Speed and knowledge as determinants of adult age differences in verbal tasks. Clin Gerontol 1993;48:P29–P36.
13.
Troyer AK, Moscovitch M, Winocur G, Alexander MP, Stuss D: Clustering and switching on verbal fluency: the effects of focal frontal- and temporal-lobe lesions. Neuropsychologia 1998;36:499–504.
14.
Ruff RM, Light RH, Parker SB, Levin HS: The psychological construct of word fluency. Brain Lang 1997;57:394–405.
15.
Salthouse TA: The processing-speed theory of adult age differences in cognition. Psychol Rev 1996;103:403–428.
16.
Kemps E, Wilsdon A: Preliminary evidence for a role for impulsivity in cognitive disinhibition in bulimia nervosa. J Clin Exp Neuropsychol 2010;32:515–521.
17.
Hasher L, Stoltzfus ER, Zacks RT, Rypma B: Age and inhibition. J Exp Psychol Learn Mem Cogn 1991;17:163–169.
18.
Wecker NS, Kramer JH, Hallam BJ, Delis DC: Mental flexibility: age effects on switching. Neuropsychology 2005;19:345–352.
19.
Kray J, Lindenberger U: Adult age differences in task switching. Psychol Aging 2000;15:126–147.
20.
Goh JO, Park DC: Neuroplasticity and cognitive aging: the scaffolding theory of aging and cognition. Restor Neurol Neurosci 2009;27:391–403.
21.
Aschenbrenner S, Tucha O, Lange K: Regensburg Word Fluency Test (Regensburger-Wortflüssigkeits-Test (RWT)). Göttingen, Hogrefe, 2000.
22.
Oswald WD, Fleischmann UM (eds): Neuropsychological Aging Inventory (NAI). Göttingen, Hogrefe, 2006.
23.
Reitan RM: Trail Making Test. Manual for Administration and Scoring. South Tucson/AZ, Reitan Neuropsychology Laboratory, 1992.
24.
Zimmermann P, Fimm B: Test Battery for Attention Performance (TAP). Würselen, Psytest, 2007.
25.
Dobbs AR, Rule BG: Adult age differences in working memory. Psychol Aging 1989;4:500–503.
26.
Helmstaedter C, Lendt M, Lux S: Verbaler Lern- und Merkfähigkeitstest. Göttingen, Beltz, 2001.
27.
Rey A: L’examen clinique en psychologie. Paris, PUF, 1958, 1964.
28.
Sheikh JI, Yesavage JA: Geriatric Depression Scale (GDS): Recent evidence and development for a shorter version. Clin Gerontol 1986;5:165–173.
29.
Laux L, Glanzmann P, Schffner P, Spielberger CD: The State-Trait-Anxiety Inventory (das State-Trait-Angstinventar (STAI)). Weinheim, Beltz, 1981.
30.
Karbach J, Kray J: How useful is executive control training? Age differences in near and far transfer of task-switching training. Dev Sci 2009;12:978–990.
31.
Bherer L, Kramer AF, Peterson MS, Colcombe S, Erickson K, Becic E: Training effects on dual-task performance: are there age-related differences in plasticity of attentional control? Psychol Aging 2005;20:695–709.
32.
Stine-Morrow EA, Parisi JM, Morrow DG, Park DC: The effects of an engaged lifestyle on cognitive vitality: a field experiment. Psychol Aging 2008;23:778–786.
33.
Tomer R, Levin BE: Differential effects of aging on two verbal fluency tasks. Percept Motor Skills 1993;76:465–466.
34.
Van der Elst W, Van Boxtel MP, Jolles J: Occupational activity and cognitive aging: a case-control study based on the Maastricht Aging Study. Exp Aging Res 2012;38:315–329.
35.
Horn JL, Cattell RB: Age differences in fluid and crystallized intelligence. Acta Psychol (Amst) 1967;26:107–129.
36.
Galasko D, Klauber MR, Hofstetter CR, Salmon DP, Lasker B, Thal LJ: The mini-mental state examination in the early diagnosis of Alzheimer’s disease. Arch Neurol 1990;47:49–52.
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