... that the majority of families have mutations in Alport syndrome genes COL4A3/4/5. We have collected data from over 50 Turkish Cypriot families in whom kidney disease appears to follow an autosomal dominant pattern, and looked for pathological variants in these genes. Methods: Probands from 55 families underwent...

... nephropathy Postinfectious glomerulonephritis Alport syndrome Collagen type III glomerulopathy Electron microscopy (EM), together with routine light microscopy (LM) and immunofluorescence (IF) and/or immunohistochemistry, has long been an essential component in the diagnostic workup of medical...

... or advertisements. Hereditary nephritis Thin glomerular basement membrane Alport syndrome Type IV collagen Thin GBM lesion is most commonly the result of an autosomal recessive COL4A3 or COL4A4 mutations. Of note, thin GBM can also be an initial early finding in some patients developing Alport...