The objective was to determine whether mismatch negativity (MMN) is suitable to supplement subjective psychometric subtests of central hearing. We assessed 13 healthy children and 32 children with central auditory processing disorder (CAPD). Three different types of sound deviants were presented in a multi-deviant MMN design. At group level, the incidence of MMN was always higher in clinically diagnosed controls. Children with better results in the subtest Auditory Memory Span had a higher incidence of MMN. The controls also had peak latencies that occurred significantly earlier in frontal, central and temporal electrode sites. The area under the curve (AUC) displayed an asymmetric distribution in CAPD children, who tended to have a left-hemispheric dominance. AUC, peak latency, and the incidence of MMN reflected the discriminative ability of CAPD children. Hence, these characteristics could be used for investigating children with deficits in central hearing and can supplement psychometric tests.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.